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09:21
Optimized Management of Endovascular Treatment for Acute Ischemic Stroke
Published on: January 18, 2018
Stroke management.
Elizabeth Warburton1, Josef A Alawneh, Philip L Clatworthy
1Neuroscience's Addenbrookes Hospital, Cambridge, UK.
BMJ Clinical Evidence
|June 11, 2011
Summary
This systematic review examines treatments for acute stroke, including specialized care and medical interventions like aspirin and thrombolysis. It evaluates the effectiveness and safety of various stroke treatments based on 41 studies.
Area of Science:
- Neurology
- Clinical Medicine
- Evidence-Based Practice
Background:
- Stroke is a leading cause of death globally, affecting millions annually.
- Ischaemic strokes, caused by artery blockages, constitute 80% of acute cases.
- Cerebral haemorrhages account for the remaining stroke cases.
Purpose of the Study:
- To systematically review the effects of specialized care in acute stroke patients.
- To evaluate the efficacy and safety of medical treatments for acute ischaemic stroke.
- To assess interventions including decompressive hemicraniectomy and surgical evacuation for intracerebral haematomas.
Main Methods:
- Conducted a systematic review of 41 studies including systematic reviews, RCTs, and observational studies.
- Searched major databases (Medline, Embase, Cochrane Library) up to August 2010.
- Included harms alerts from regulatory agencies like the FDA and MHRA.
Main Results:
- Identified evidence for various interventions including blood pressure reduction, aspirin, and thrombolysis.
- Evaluated the effectiveness of specialized stroke care and decompressive hemicraniectomy.
- Assessed systemic anticoagulation and neuroprotective agents.
Conclusions:
- Presents information on the effectiveness and safety of multiple acute stroke interventions.
- Highlights the importance of evidence-based treatments for stroke management.
- Provides a comprehensive overview of interventions for ischaemic and haemorrhagic stroke.
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