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Related Experiment Video

Updated: Jun 1, 2026

A Primary Human Trophoblast Model to Study the Effect of Inflammation Associated with Maternal Obesity on Regulation of Autophagy in the Placenta
11:44

A Primary Human Trophoblast Model to Study the Effect of Inflammation Associated with Maternal Obesity on Regulation of Autophagy in the Placenta

Published on: September 27, 2017

Maternal obesity and nonstress testing.

Steffen Brown1, Michael D Wolfe, Rebecca Coalson

  • 1Department of Obstetrics and Gynecology, University of New Mexico Health Sciences Center, Albuquerque, New Mexico 87131-0001, USA. Stbrown@salud.unm.edu

American Journal of Perinatology
|June 11, 2011
PubMed
Summary
This summary is machine-generated.

Maternal obesity does not impact nonstress test (NST) results or duration. Obese women underwent more NSTs per patient, but test performance and reactive result times remained unaffected by obesity.

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Area of Science:

  • Obstetrics and Gynecology
  • Maternal-Fetal Medicine
  • Fetal Monitoring

Background:

  • Maternal obesity is a growing concern in pregnancy.
  • Its impact on fetal well-being assessments, such as nonstress tests (NSTs), requires further clarification.
  • Understanding these effects is crucial for optimizing prenatal care.

Purpose of the Study:

  • To investigate the influence of maternal obesity on nonstress test (NST) characteristics and outcomes.
  • To determine if maternal obesity affects the time required to achieve a reactive NST result.
  • To compare the frequency of NSTs performed in obese versus nonobese pregnant women.

Main Methods:

  • Prospective cohort study over 1 year.
  • Included 2026 NSTs from 575 women with singleton gestations (≥ 32 weeks) and no fetal anomalies.
  • Maternal Body Mass Index (BMI) classified at the first prenatal visit; primary outcome was time to reactive NST.

Main Results:

  • Obesity did not increase the likelihood of nonreactive NST results.
  • Mean duration to a reactive NST result was not significantly affected by maternal obesity, even after adjusting for diabetes and gestational age.
  • Obese women had a higher average number of NSTs per patient (3.9 vs. 3.1, P < 0.01).

Conclusions:

  • Maternal obesity does not impair the ability to perform a nonstress test (NST) or prolong the time to a reactive result.
  • While obese women may require more frequent NSTs, the test's efficacy in assessing fetal well-being is not compromised by their weight status.
  • These findings support the continued use of NSTs in obese pregnancies without modification based solely on BMI.