Delayed implant procedure using deproteinized bovine bone mineral: A report of 109 consecutive cases
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Updated: Jun 1, 2026

Biological Compatibility Profile on Biomaterials for Bone Regeneration
Published on: November 16, 2018
Wayne A Aldredge1, Richard Nejat
1Department of Periodontics and Implantology, Stony Brook University, Long Island, New York, USA.
Purpose:
The purpose of this consecutive case series was to analyze the success rate of endosseous implants placed into deproteinized bovine bone mineral (DBBM) maxillary and mandibular grafted extraction sites during a 48-month period.
Methods:
During a 48-month period, 69 consecutive patients presented with 109 nonrestorable teeth. The teeth were extracted and the sites grafted with DBBM, and the extraction sockets were allowed to heal for an average of 6 months. Following healing, implants were placed in the grafted sites. Osseointegration was assessed based on a lack of mobility and a radiographic evaluation.
Results:
Implants were placed in all of the 109 grafted sites with no graft failures. No implant was mobile at uncovering. All 109 implants are currently loaded and have been in function for 6 months to 65 months with an average of 2 years for a 100% cumulative success rate. Marginal soft-tissue levels remain stable.
Conclusion:
The delayed implant approach using DBBM is a predictable treatment modality, resulting in long-term implant stability and predictable esthetic results.

