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Updated: Jun 1, 2026

Analysis of Volatile and Oxidation Sensitive Compounds Using a Cold Inlet System and Electron Impact Mass Spectrometry
Published on: September 5, 2014
Fragment-Free Mass Spectrometric Analysis with Jet Cooling/VUV Photoionization
E Nir1, H E Hunziker, M S de Vries
1Department of Chemistry, The Hebrew University of Jerusalem, Jerusalem 91904, Israel.
Abstract:
We show that it is possible to obtain fragment-free mass spectra of large molecules by a combination of laser desorption, jet cooling, and VUV single-photon photoionization. The ability to obtain parent molecular masses is particularly important for the analysis of mixtures, such as combinations of fully saturated hydrocarbons. By varying the cooling conditions, we can also achieve partial fragmentation in order to obtain further structural information. The use of different wavelengths provides additional selectivity between aromatic and aliphatic compounds.
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