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Related Experiment Video

Updated: Jun 1, 2026

Glass-Based Devices to Generate Drops and Emulsions

Glass-Based Devices to Generate Drops and Emulsions

Published on: April 5, 2022

A design for low-flow sheathless electrospray emitters.

D R Barnidge¹, S Nilsson, K E Markides

¹Department of Analytical Chemistry, Uppsala University, Box 531, 751 21 Uppsala, Sweden.

Analytical Chemistry

|June 14, 2011

Summary

This summary is machine-generated.

A novel "fairy dust" technique creates durable, sheathless electrospray emitters from fused-silica capillaries. These emitters provide stable electrospray over a wide flow rate range, offering a simple and long-lasting solution.

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Last Updated: Jun 1, 2026

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Area of Science:

Analytical Chemistry
Materials Science

Background:

Traditional electrospray emitters often require complex designs and can degrade over time.
Achieving stable electrospray, especially at varying flow rates, presents a persistent challenge in analytical instrumentation.

Purpose of the Study:

To develop a simple, robust, and long-lasting sheathless electrospray emitter.
To enable the creation of integrated "all-in-one" microcolumn-emitter systems.

Main Methods:

A novel fabrication method, termed the "fairy dust" technique, was employed.
This method involves adhering 2-μm gold particles to the tip of a fused-silica capillary, avoiding metallization.
The emitters were tested for stability across a range of flow rates (30 nL/min to 1 mL/min).

Main Results:

The developed emitters demonstrated highly stable electrospray performance.
The emitters exhibited durability and effectively unlimited lifetimes.
Stable electrospray was achieved without the need for nebulizing gas.
The design successfully eliminated unwanted void volumes in microcolumn-emitter systems.

Conclusions:

The "fairy dust" technique offers a straightforward and effective approach to producing durable sheathless electrospray emitters.
These emitters are suitable for a wide range of applications, including integrated microfluidic systems.
The simplicity and robustness of the design address key limitations in current electrospray technology.