Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

An atomic layer deposition reactor with dose quantification for precursor adsorption and reactivity studies.

The Review of scientific instruments·2013

Same author

Calixarenes. 22. Synthesis, properties, and metal complexation of aminocalixarenes.

Journal of the American Chemical Society·2011

Same author

Selective metals determination with a photoreversible spirobenzopyran.

Analytical chemistry·2011

Same author

Capillary Electrokinetic Chromatography Employing p-(Carboxyethyl)calix[n]arenes as Running Buffer Additives.

Analytical chemistry·2011

Same author

A new method of producing fused ring structures related to the steroids; a synthesis of equilenin.

Journal of the American Chemical Society·2010

Same author

Bio-organism sensing via surface enhanced Raman spectroscopy on controlled metal/polymer nanostructured substrates.

Biointerphases·2010

Search research articles

Related Experiment Video

Updated: Jun 1, 2026

Sample Preparation in Quartz Crystal Microbalance Measurements of Protein Adsorption and Polymer Mechanics

Sample Preparation in Quartz Crystal Microbalance Measurements of Protein Adsorption and Polymer Mechanics

Published on: January 22, 2020

Calixarene monolayers as quartz crystal microbalance sensing elements in aqueous solution.

M T Cygan¹, G E Collins, T D Dunbar

¹Chemistry Division, Naval Research Laboratory, Code 6116, Washington, D.C. 20375-5342, 185 Materials Research Institute, The Pennsylvania State University, University Park, Pennsylvania 16802, and Texas Christian University, P.O. Box 32908, Fort Worth, Texas 76129.

Analytical Chemistry

|June 14, 2011

Summary

p-tert-butylcalix[4]arenetetrathiolate (BCAT) monolayers show high selectivity for alkylbenzenes in aqueous sensors. These calixarene-based sensors offer superior molecular recognition compared to other film types.

More Related Videos

Dissipative Microgravimetry to Study the Binding Dynamics of the Phospholipid Binding Protein Annexin A2 to Solid-supported Lipid Bilayers Using a Quartz Resonator

Dissipative Microgravimetry to Study the Binding Dynamics of the Phospholipid Binding Protein Annexin A2 to Solid-supported Lipid Bilayers Using a Quartz Resonator

Published on: November 1, 2018

Epitaxial Nanostructured α-Quartz Films on Silicon: From the Material to New Devices

Epitaxial Nanostructured α-Quartz Films on Silicon: From the Material to New Devices

Published on: October 6, 2020

Related Experiment Videos

Last Updated: Jun 1, 2026

Sample Preparation in Quartz Crystal Microbalance Measurements of Protein Adsorption and Polymer Mechanics

Sample Preparation in Quartz Crystal Microbalance Measurements of Protein Adsorption and Polymer Mechanics

Published on: January 22, 2020

Dissipative Microgravimetry to Study the Binding Dynamics of the Phospholipid Binding Protein Annexin A2 to Solid-supported Lipid Bilayers Using a Quartz Resonator

Dissipative Microgravimetry to Study the Binding Dynamics of the Phospholipid Binding Protein Annexin A2 to Solid-supported Lipid Bilayers Using a Quartz Resonator

Published on: November 1, 2018

Epitaxial Nanostructured α-Quartz Films on Silicon: From the Material to New Devices

Epitaxial Nanostructured α-Quartz Films on Silicon: From the Material to New Devices

Published on: October 6, 2020

Area of Science:

Supramolecular Chemistry
Chemical Sensing
Surface Science

Background:

Molecular recognition elements are crucial for developing in situ aqueous chemical sensors.
Calixarene derivatives offer unique structural properties for self-assembly and molecular interactions.

Purpose of the Study:

To evaluate p-tert-butylcalix[4]arenetetrathiolate (BCAT) monolayers as molecular recognition elements for aqueous chemical sensing.
To compare the sensing performance of BCAT monolayers with p-tert-butylcalix[4]arene (BCA) and decanethiolate (DT) films.

Main Methods:

Fabrication and characterization of BCAT monolayers on Au{111} using spectroscopic and wetting studies.
Quartz crystal microbalance (QCM) sensors were employed to assess the chemical specificity of various monolayers and thin films.
Analysis of sensor response to aromatic and aliphatic analytes in aqueous solutions.

Main Results:

BCAT monolayers exhibit preferential orientation with phenyl rings parallel to the surface normal.
BCAT sensors demonstrated high selectivity towards alkylbenzenes, outperforming BCA thin films and DT monolayers.
Differences in molecular differentiation were attributed to film order and cavitation effects.

Conclusions:

BCAT monolayers are effective molecular recognition elements for selective aqueous chemical sensing.
The ordered structure of BCAT monolayers plays a significant role in molecular recognition.
Calixarene-based films offer a promising platform for advanced sensor development.