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Related Concept Videos

Intestinal Obstruction II: Pathophysiology01:07

Intestinal Obstruction II: Pathophysiology

Intestinal obstruction triggers a series of physiological responses, starting with gas and fluid accumulation in the bowel segment proximal to the obstruction, leading to distension. This distended intestine compresses the diaphragm, hindering lung expansion and potentially leading to reduced respiratory effort, atelectasis, and pneumonia.To overcome the blockage, the gut intensifies contractions, causing colicky abdominal pain, nausea, and vomiting, which reduces fluid and food intake and...
Acute Pancreatitis II: Clinical Manifestations and Management01:30

Acute Pancreatitis II: Clinical Manifestations and Management

Acute pancreatitis presents a complex medical emergency characterized by rapid onset inflammation of the pancreas, demanding timely diagnosis and management to prevent complications. The condition primarily manifests through severe upper abdominal pain that often radiates to the back. This pain intensifies following the consumption of fatty foods. Accompanying symptoms such as nausea, vomiting, abdominal distention, fever, dyspnea, cyanosis, and jaundice can vary in intensity but significantly...
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Acute pancreatitis is the sudden inflammation of the pancreas caused by the early activation of digestive enzymes, leading to the autodigestion of pancreatic tissue. This results in local inflammation and, in severe cases, systemic complications.EtiologyUnderstanding the underlying causes is crucial, as identifying the etiology guides treatment and anticipates complications. Acute pancreatitis can be triggered by various factors, typically grouped into the following clinical categories.Biliary...
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Pancreatitis is inflammation of the pancreas, an organ located behind the stomach. It can be either acute or chronic.
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Appendicitis01:19

Appendicitis

Appendicitis is an acute inflammatory condition of the vermiform appendix, most commonly caused by obstruction of its lumen. The appendix is a narrow, blind-ended pouch that extends from the cecum, making it particularly prone to obstruction. Causes include fecaliths, lymphoid hyperplasia (often after viral infections), parasites, tumors, or foreign bodies. This obstruction initiates a cascade of pathological changes.Luminal Obstruction and Early InflammationAfter obstruction, normal mucosal...
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The pathophysiology of acute pancreatitis centers on injury to pancreatic acinar cells, which initiates a cascade of harmful intracellular events.This injury leads to premature activation of trypsinogen to trypsin in the pancreas. Trypsin then activates other digestive enzymes, such as chymotrypsin, elastase, and phospholipase A2, which begin breaking down pancreatic tissue. The resulting autodigestion causes local inflammation, tissue swelling, hemorrhage, and fat necrosis.Injured acinar cells...

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Surgical Closure of Equine Abdomen, Prevention, and Management of Incisional Complications
09:41

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Published on: May 10, 2024

Peritonitis in horses: 55 cases (2004-2007).

Nóra Nógrádi1, Balázs Tóth, Katherine Cole Macgillivray

  • 1University of California William R. Pritchard Veterinary Medical Teaching Hospital Davis, One Shields Ave. Davis, CA 95616, USA. nnogradi@ucdavis.edu

Acta Veterinaria Hungarica
|June 14, 2011
PubMed
Summary

Prognosis for equine peritonitis depends on initial hydration and surgical intervention, not common clinical signs. Early detection and management are key for better survival rates in horses with this condition.

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Published on: December 18, 2010

Area of Science:

  • Veterinary Medicine
  • Equine Health
  • Internal Medicine

Background:

  • Peritonitis in horses often has an unclear prognosis.
  • Limited data exists on factors influencing equine peritonitis outcomes.

Purpose of the Study:

  • Identify common clinical and clinicopathologic findings in horses with peritonitis.
  • Determine prognostic factors associated with survival in equine peritonitis cases.

Main Methods:

  • Retrospective analysis of 55 horses diagnosed with and treated for peritonitis.
  • Evaluation of clinical signs, clinicopathologic data, and treatment outcomes.
  • Multivariate logistic regression to identify significant prognostic factors.

Main Results:

  • Common findings included tachycardia, increased peritoneal fluid, altered mucous membranes, and bacterial presence.
  • E. coli was the most frequent isolate (37%).
  • Survival rates varied by treatment: 93% medical, 81% abdominal lavage, 46% surgical. Initial hematocrit and surgical intervention were linked to non-survival.

Conclusions:

  • Prognosis for equine peritonitis (without GI rupture) hinges on initial hydration, surgical intervention, and secondary complications.
  • Common clinical signs and clinicopathologic findings showed little correlation with survival.
  • Further research on hydration, perfusion, and abdominal lavage is warranted.