[Diagnosis of different stages of epileptogenesis by fractal EEG analysis]

The diagnostic evaluation of brain activity disturbances using fractal EEG analysis was performed in 95 patients with different stages of epileptogenesis. The control group included 30 normals. Authors have shown the possibility to determine phases of the development of epileptic process according to the peculiarities of the dynamics of main EEG band power fluctuations with the spectrum in the form of 1/f(β). The disturbances of alpha, theta, beta-1 and beta-2 band characteristics at the preclinical (initial) and clinical stages of epileptogenesis were revealed. There were topographical changes in indexes of fractal chaos linked with the growth of brain epileptization. The parameters of fractal fluctuations in alpha-band power proved to be the most informative for the objectification of the degree of intensity of epileptic disturbances. The method of fractal EEG analysis is concluded to be highly effective for diagnosis of all stages of epileptogenesis.