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Updated: Jun 1, 2026

Catheter Ablation in Combination With Left Atrial Appendage Closure for Atrial Fibrillation
Published on: February 26, 2013
Peripheral artery disease and atrial fibrillation: a potentially dangerous combination
Francesco Violi1, Gregory Y H Lip, Stefania Basili
1Divisione di I Clinica Medica, Sapienza-University of Rome, Rome, Italy. francesco.violi@uniroma1.it
Abstract:
Atrial fibrillation (AF) is commonly associated with a significant increase in stroke and thromboembolic risk. Many patients with AF have associated atherothrombosis given the many risk factors for atherosclerosis that also predispose to AF. Vascular disease, whether peripheral artery disease or myocardial infarction, contributes to the increased risk of stroke and thromboembolism, and has been included in stroke risk assessment schema. This review analyzes the interplay between AF and peripheral artery disease in relation to their associated pathophysiology, as well as epidemiological data linking both conditions and the associated thromboembolic complications conferred by the presence of both.
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