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Osteoporosis treatment: an evidence-based approach
Kelly R Ragucci1, Sarah P Shrader
1South Carolina College of Pharmacy, Medical University of South Carolina, Charleston, South Carolina 29425, USA. raguccik@musc.edu
Osteoporosis management involves lifestyle changes like adequate calcium, vitamin D, and exercise, alongside various nonhormonal medications. Clinicians must stay updated on guidelines for effective, patient-specific osteoporosis treatment.
Area of Science:
- Bone metabolism and skeletal health.
Background:
- Osteoporosis significantly reduces bone mass and quality, increasing fracture risk.
- Current clinical practice requires counseling on lifestyle modifications and pharmacological interventions.
Purpose of the Study:
- To review current evidence and guidelines for osteoporosis prevention and treatment.
- To emphasize the importance of evidence-based, individualized pharmacological decisions for nurses.
Main Methods:
- Review of nonhormonal pharmacological options for osteoporosis.
- Consideration of recent guidelines from the National Osteoporosis Foundation and American Association of Clinical Endocrinologists.
Main Results:
- Lifestyle factors (calcium, vitamin D, exercise, reduced alcohol/caffeine, smoking cessation) are crucial.
- Pharmacological options include bisphosphonates, calcitonin, raloxifene, teriparatide, and denosumab.
Conclusions:
- Clinicians must be aware of the latest evidence supporting various osteoporosis treatment modalities.
- Nurses play a vital role in making cost-effective, evidence-based therapeutic choices tailored to individual patients.
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