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An unusual cause of failure to thrive in a child

Purnima Samayam1, Ravi Chander B, Sudha Reddy V R

  • 1Department of Paediatrics, M.V.J. Medical College and Research Hospital, Dandupalya, Kolathur Post, Kolar Highway, Hoskote, Bengaluru 562114, Karnataka, India. drpurnimas@yahoo.com

The National Medical Journal of India
|June 15, 2011
PubMed

Insights

Classic Bartter syndrome can mimic malnutrition in children. Early diagnosis of this renal tubular disorder is crucial for proper treatment and improved growth outcomes.

Area of Science:

  • Pediatric Nephrology
  • Genetics and Rare Diseases

Background:

  • Classic Bartter syndrome is a rare inherited renal tubular disorder.
  • It can present with failure to thrive, often misdiagnosed as malnutrition, especially in resource-limited settings.

Observation:

  • A 5-year-old boy, asymptomatic until age 3, was repeatedly treated for protein-energy malnutrition despite adequate nutrition.
  • He exhibited persistent hypokalemia and polyuria, suggesting a renal tubular disorder.

Findings:

  • Diagnostic evaluation revealed persistent hypokalemia and polyuria, indicative of a renal tubular disorder.
  • Treatment for the underlying condition led to significant weight gain and normalized serum electrolytes.

Implications:

  • Highlights the importance of considering rare genetic disorders in pediatric failure to thrive cases.
  • Timely diagnosis and management of Bartter syndrome are essential for preventing malnutrition misdiagnosis and ensuring healthy development.

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