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Updated: May 21, 2026

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Methods for Quantitative Detection of Antibody-induced Complement Activation on Red Blood Cells
Published on: January 29, 2014
Autoimmune hemolytic anemia: mixed type-a case report.
Summary
This study presents a rare case of mixed autoimmune hemolytic anemia (AIHA) in a 12-year-old girl. The patient
Area of Science:
- Hematology
- Immunology
- Pediatrics
Background:
- Mixed autoimmune hemolytic anemia (AIHA) involves both warm and cold autoantibodies.
- Diagnosis requires specific serological findings, including IgG, C3d, and cold agglutinins.
Observation:
- A rare case of primary mixed AIHA was observed in a 12-year-old girl.
- The patient presented with symptoms indicative of AIHA.
Findings:
- The patient's AIHA was characterized by the presence of both warm and cold autoantibodies.
- Diagnostic tests confirmed IgG and C3d on red blood cells, along with cold agglutinins.
Implications:
- This case highlights the importance of comprehensive diagnostic approaches for mixed AIHA.
- Corticosteroid therapy can be effective in managing pediatric mixed AIHA.
- Further research into rare pediatric autoimmune hematological disorders is warranted.
Keywords:
Auto agglutinationAutoimmune haemolytic anemia (AIHA)CorticosteroidsDirect antiglobulin test (DAT)More Related Videos
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