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Urinary dysfunction in early and untreated Parkinson's disease
Tomoyuki Uchiyama1, Ryuji Sakakibara, Tatsuya Yamamoto
1Department of Neurology, Chiba University Graduate School of Medicine, 1-8-1 Inohana, Chuo-ku, Chiba 260-8670, Japan. uchiyama@faculty.chiba-u.jp
Journal of Neurology, Neurosurgery, and Psychiatry
|June 15, 2011
Summary
Urinary dysfunction is common in early Parkinson's disease (PD), affecting storage and voiding functions. Early diagnosis and management are crucial for improving quality of life in PD patients.
Area of Science:
- Neurology
- Urology
Background:
- Urinary dysfunction is a frequent complication in Parkinson's disease (PD).
- Limited data exists on urinary issues in early, untreated PD patients.
Purpose of the Study:
- To investigate the prevalence and characteristics of urinary dysfunction in early, untreated Parkinson's disease patients.
Main Methods:
- Fifty untreated PD patients underwent urinary questionnaires and urodynamic studies.
- Exclusion criteria applied to patients with conditions affecting urinary function.
Main Results:
- 64% reported urinary symptoms; 84% showed storage phase abnormalities on urodynamics.
- Detrusor overactivity (58%) and detrusor underactivity (50%) were common.
- Urinary findings did not correlate with gender, disease severity, or motor symptoms.
Conclusions:
- Early and untreated PD patients commonly experience urinary dysfunction, primarily storage issues.
- Subclinical voiding disorders are also prevalent.
- Abnormal findings may necessitate considering alternative diagnoses.
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