Angiotensin (1-7) induces MAS receptor internalization

Mariela M Gironacci1, Hugo P Adamo, Gerardo Corradi

  • 1Instituto de Química y Fisicoquímica Biológicas, Consejo Nacional de Investigaciones Científicas y Técnicas, Facultad de Farmacia y Bioquímica, Universidad de Buenos Aires, Junín 956, 1113 Buenos Aires, Argentina. mariela@qb.ffyb.uba.ar

Summary

Angiotensin (1-7) binding causes the Mas receptor to internalize into cells, which may explain its desensitization. This cellular process helps regulate Mas receptor activity and density.

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