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Related Concept Videos

Role of Hippocampus in Memory01:19

Role of Hippocampus in Memory

The hippocampus, a critical brain structure, plays an essential role in memory processing, particularly in the formation and retrieval of memory. This small, seahorse-shaped region is located within the medial temporal lobe, with one hippocampus in each brain hemisphere. Experimental studies involving lesions in the hippocampi of rats have demonstrated significant impairments in tasks such as object recognition and maze navigation, indicating the hippocampus involvement in both recognition and...
Working Memory01:24

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Working memory refers to a combination of components, including short-term memory and attention, that allow an individual to hold information temporarily as we perform cognitive tasks. It is an essential cognitive function that enables the execution of complex tasks such as problem-solving, comprehension, and reasoning. Unlike short-term memory, which simply involves the storage of information for a brief period, working memory involves the active manipulation and processing of this information.
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Role of Cerebellum and Prefrontal Cortex in Memory

The cerebellum, while traditionally associated with motor control, also plays a crucial role in memory, particularly in procedural memory, which involves learning motor tasks that become automatic through repetition. For example, studies have shown that when the cerebellum is damaged, individuals or animals lose the ability to learn conditioned motor responses, such as the conditioned eye-blink response in classical conditioning experiments with rabbits. This study demonstrates the cerebellum's...
Higher Mental Functions of Brain: Learning and Memory01:26

Higher Mental Functions of Brain: Learning and Memory

Memory is one of the most vital higher mental functions of the brain. Memory is closely related to learning because it enables us to retain information and experiences from our past to use them in our present life. It also helps us to remember facts, events, and skills, such as riding a bike or swimming. There are two types of memory — declarative memory, which involves memorizing facts or events, and procedural memory, which enables us to remember how to do something like writing or playing an...
Functional Brain Systems: Limbic System01:15

Functional Brain Systems: Limbic System

The limbic system, often called the "emotional brain," is a complex set of structures located deep within the brain. The intricate network of the limbic system supports a wide range of psychological functions, from emotional regulation to memory formation and sensory processing. This functional brain region encompasses specific parts of the diencephalon and the cerebrum, integrating the higher mental functions of the cerebral cortex with the primitive emotional responses of the deep brain...
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Related Experiment Video

Updated: Jun 1, 2026

Longitudinal Two-Photon Imaging of Dorsal Hippocampal CA1 in Live Mice
09:34

Longitudinal Two-Photon Imaging of Dorsal Hippocampal CA1 in Live Mice

Published on: June 19, 2019

Working memory and the hippocampus.

Alan Baddeley1, Christopher Jarrold, Faraneh Vargha-Khadem

  • 1Department of Psychology, University of York,Heslington, York YO10 5DD, UK. ab50@york.ac.uk

Journal of Cognitive Neuroscience
|June 16, 2011
PubMed
Summary
This summary is machine-generated.

This study investigated the hippocampus's role in working memory. Despite significant hippocampal volume reduction, Jon demonstrated high performance across visuospatial and verbal tasks, challenging previous findings.

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Combined Mechanical and Enzymatic Dissociation of Mouse Brain Hippocampal Tissue

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Related Experiment Videos

Last Updated: Jun 1, 2026

Longitudinal Two-Photon Imaging of Dorsal Hippocampal CA1 in Live Mice
09:34

Longitudinal Two-Photon Imaging of Dorsal Hippocampal CA1 in Live Mice

Published on: June 19, 2019

Assessment of Memory Function in Pilocarpine-induced Epileptic Mice
13:34

Assessment of Memory Function in Pilocarpine-induced Epileptic Mice

Published on: June 4, 2020

Combined Mechanical and Enzymatic Dissociation of Mouse Brain Hippocampal Tissue
07:14

Combined Mechanical and Enzymatic Dissociation of Mouse Brain Hippocampal Tissue

Published on: October 21, 2021

Area of Science:

  • Neuroscience
  • Cognitive Psychology

Background:

  • The hippocampus is implicated in visuospatial and relational working memory.
  • Previous research suggests hippocampal damage impairs these functions.

Purpose of the Study:

  • To test the hippocampus's role in working memory generality.
  • To investigate working memory components in an individual with hippocampal volume reduction.

Main Methods:

  • Assessed working memory in Jon, with a 50% bilateral hippocampal volume reduction.
  • Compared Jon's performance to 48 college students.
  • Utilized four complex working memory span tasks combining storage and processing.

Main Results:

  • Jon exhibited consistently high performance across all tested working memory tasks.
  • His performance on component storage and processing was also high.

Conclusions:

  • Findings challenge the necessity of the hippocampus for general working memory tasks.
  • Discrepancies may relate to task demands on relational memory or processing types (egocentric vs. allocentric).