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Streptococcal Pharyngitis

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Related Experiment Video

Updated: Jun 1, 2026

A Murine Model of Fetal Exposure to Maternal Inflammation to Study the Effects of Acute Chorioamnionitis on Newborn Intestinal Development
08:50

A Murine Model of Fetal Exposure to Maternal Inflammation to Study the Effects of Acute Chorioamnionitis on Newborn Intestinal Development

Published on: June 24, 2020

Chorioamnionitis: from pathogenesis to treatment.

M J Czikk1, F P McCarthy, K E Murphy

  • 1Department of Obstetrics and Gynaecology, Mount Sinai Hospital, University of Toronto, Toronto, ON, Canada. mczikk@mtsinai.on.ca

Clinical Microbiology and Infection : the Official Publication of the European Society of Clinical Microbiology and Infectious Diseases
|June 16, 2011
PubMed
Summary
This summary is machine-generated.

Chorioamnionitis, an infection causing maternal and neonatal illness, often results from ascending infections and premature rupture of membranes. New biomarkers are needed for early risk prediction and improved treatment strategies.

Related Experiment Videos

Last Updated: Jun 1, 2026

A Murine Model of Fetal Exposure to Maternal Inflammation to Study the Effects of Acute Chorioamnionitis on Newborn Intestinal Development
08:50

A Murine Model of Fetal Exposure to Maternal Inflammation to Study the Effects of Acute Chorioamnionitis on Newborn Intestinal Development

Published on: June 24, 2020

Area of Science:

  • Obstetrics and Gynecology
  • Infectious Diseases
  • Neonatology

Background:

  • Chorioamnionitis is inflammation of the amniochorionic membrane.
  • It is a major cause of maternal and neonatal morbidity.
  • Often linked to ascending infections and premature rupture of membranes.

Purpose of the Study:

  • To review the causes, consequences, and current management of chorioamnionitis.
  • To highlight the need for improved diagnostic and therapeutic approaches.

Main Methods:

  • Literature review of chorioamnionitis.
  • Analysis of causative organisms and treatment modalities.

Main Results:

  • Chorioamnionitis is frequently polymicrobial, with common pathogens including Ureaplasma urealyticum, Mycoplasma hominis, and Gram-negative anaerobes.
  • Current treatments involve antimicrobials, antipyretics, expedited delivery, and supportive care.

Conclusions:

  • Further research is essential to identify early biomarkers for risk prediction.
  • Developing novel treatment and prevention strategies is crucial for better maternal and neonatal outcomes.