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Related Concept Videos

Olfaction01:25

Olfaction

The sense of smell is achieved through the activities of the olfactory system. It starts when an airborne odorant enters the nasal cavity and reaches olfactory epithelium (OE). The OE is protected by a thin layer of mucus, which also serves the purpose of dissolving more complex compounds into simpler chemical odorants. The size of the OE and the density of sensory neurons varies among species; in humans, the OE is only about 9-10 cm2.
The olfactory receptors are embedded in the cilia of the...

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Related Experiment Video

Updated: Jun 1, 2026

Localization of Odorant Receptor Genes in Locust Antennae by RNA In Situ Hybridization
09:30

Localization of Odorant Receptor Genes in Locust Antennae by RNA In Situ Hybridization

Published on: July 13, 2017

Lobster olfactory genomics.

Timothy S McClintock1, Barry W Ache, Charles D Derby

  • 1Department of Physiology, Cellular and Molecular Neuroscience of Sensory Systems Training Program, University of Kentucky Lexington, KY 40536-0298, USA.

Integrative and Comparative Biology
|June 16, 2011
PubMed
Summary
This summary is machine-generated.

Lobsters serve as excellent models for studying olfaction, with new genomic research identifying key genes and cell types in their olfactory organs. This study reveals novel glands and functions, advancing our understanding of sensory biology.

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Area of Science:

  • * Crustacean biology
  • * Neuroscience
  • * Genomics

Background:

  • * Lobsters possess highly specialized olfactory systems, making them valuable models for olfaction research.
  • * Advances in genomics and physiological genomics enhance the study of lobster olfactory organs.

Purpose of the Study:

  • * To identify functionally significant genes within the lobster olfactory organ using genomic approaches.
  • * To characterize cell types and discover new structures and functions within the olfactory system.

Main Methods:

  • * Construction of a subtracted cDNA library from the mature zone of the olfactory organ.
  • * Application of three physiological genomics experiments.
  • * Analysis of gene expression patterns for cell identification and functional discovery.

Main Results:

  • * Identification of specific markers for three previously indistinguishable cell types.
  • * Discovery of a marker for reactive epithelial cells involved in tissue replacement and regeneration.
  • * Unveiling of the aesthetasc tegumental gland, crucial for olfactory organ maintenance.
  • * Suggestion of a novel endocrine/paracrine role for auxiliary cells in sensory units.
  • * Identification of candidate genes for olfactory transduction, presynaptic modulation, and neuromodulation.

Conclusions:

  • * Genomic and physiological genomics approaches significantly advance the study of lobster olfaction.
  • * The research reveals novel cellular, glandular, and functional aspects of the lobster olfactory system.
  • * Findings provide insights into olfactory transduction, neural modulation, and tissue regeneration.