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Updated: Jun 1, 2026

Establishment and Characterization of UTI and CAUTI in a Mouse Model
Published on: June 23, 2015
[Urinary tract infections in adults]
Stéphane Emonet1, Stephan Harbarth, Christian van Delden
1Service des maladies infectieuses, Departement des specialites de medecine, Direction medicale HUG, 1211 I Genève.uge.ch. stephane.p.emonet@hcuge.ch
Urinary tract infections (UTI) are common. New guidelines recommend fosfomycin and furadantine over quinolones due to rising antibiotic resistance, impacting adult UTI management.
Area of Science:
- Urology
- Infectious Diseases
- General Practice
Context:
- Urinary tract infections (UTI) represent a significant clinical challenge frequently encountered in primary care settings.
- Quinolone antibiotics have been historically overused for UTI treatment, contributing to the development of antimicrobial resistance.
- Emerging resistance patterns necessitate updated clinical guidelines for effective UTI management.
Purpose:
- To review the current epidemiology and pathogenesis of urinary tract infections in adults.
- To outline diagnostic approaches for identifying UTIs.
- To discuss updated treatment strategies, emphasizing newer antibiotic recommendations.
Summary:
- This review examines the epidemiology, pathogenesis, diagnosis, and treatment of adult urinary tract infections.
- It highlights the shift in management guidelines from quinolones to fosfomycin and furadantine due to increasing antibiotic resistance.
- The article provides a comprehensive overview for general practitioners managing uncomplicated UTIs.
Impact:
- Provides evidence-based recommendations for optimizing antibiotic selection in UTI treatment.
- Aims to curb the further emergence of antibiotic resistance by promoting judicious use of antimicrobials.
- Enhances clinical decision-making for healthcare providers managing adult patients with urinary tract infections.
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