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Updated: May 31, 2026
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Transthoracic Speckle Tracking Echocardiography for the Quantitative Assessment of Left Ventricular Myocardial Deformation
Published on: October 20, 2016
Subclinical left ventricular dysfunction in Behcet's disease assessed by two-dimensional speckle tracking
Julide Yagmur1, Serpil Sener, Nusret Acikgoz
1Department of Cardiology, Faculty of Medicine, Inonu University, Malatya, Turkey. julideyagmur@hotmail.com
Summary
Speckle tracking echocardiography detects impaired longitudinal systolic function in Behcet
Area of Science:
- Cardiology
- Echocardiography
- Behcet's Disease
Background:
- Behcet's disease (BD) can affect the cardiovascular system, potentially leading to myocardial dysfunction.
- Early detection of subclinical cardiac involvement is crucial for managing BD patients.
Purpose of the Study:
- To evaluate left ventricular (LV) systolic strain using speckle tracking echocardiography (STE) for early detection of myocardial dysfunction in BD patients.
- To investigate the relationship between LV systolic strain and N-terminal pro-B type natriuretic peptide (NT-proBNP) levels.
Main Methods:
- Speckle tracking echocardiography (STE) was used to assess longitudinal and circumferential systolic strain in 32 BD patients and 27 controls.
- N-terminal pro-B type natriuretic peptide (NT-proBNP) levels were measured in all participants.
Main Results:
- BD patients showed significantly reduced longitudinal systolic strain compared to controls (P < 0.0001).
- Circumferential systolic strain did not differ significantly between groups (P = 0.62).
- NT-proBNP levels were significantly higher in BD patients (P = 0.003), correlating independently with impaired longitudinal strain (R = 0.603, P = 0.001).
Conclusions:
- Longitudinal myocardial systolic function, assessed by STE, is impaired in BD patients, indicating subclinical ventricular dysfunction.
- Elevated NT-proBNP levels may serve as a biomarker for this subclinical dysfunction in BD.
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