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Updated: May 31, 2026

An In Vivo Assessment of Blood-Brain Barrier Disruption in a Rat Model of Ischemic Stroke
Published on: March 11, 2018
[Edema in nervous tissue studied on model of hemorrhagic stroke in vitro]
Abstract:
The development of edema in the survival olfactory cortex slices under the long-term action of autoblood has been studied by monitoring the bioelectric activity of nervous cells. The level of disorder in electrogenesis of cells was revealed by comparing the focal potentials with their control values; the degree of the nervous tissue swelling in various periods of autoblood action was determined by weighing. In the model of hemorrhagic stroke, the dependence of edema growth on the level of activity of ionotropic glutamate receptors has been determined using the pharmacological blockade technique.
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