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Mitral and tricuspid annular velocities in constrictive pericarditis and restrictive cardiomyopathy: correlation with

Joon Hyouk Choi1, Jin-Oh Choi, Dong Ryeol Ryu

  • 1Department of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea.

JACC. Cardiovascular Imaging
|June 18, 2011
PubMed

Insights

Reduced ratios of lateral to septal early diastolic mitral annular velocity (E') can help diagnose constrictive pericarditis (CP). This study compared E' velocities in CP, restrictive cardiomyopathy, and controls, finding lower lateral and tricuspid E' ratios in CP patients.

Area of Science:

  • Cardiology
  • Echocardiography
  • Cardiac Imaging

Background:

  • Septal early diastolic mitral annular velocity (SE') can differentiate constrictive pericarditis (CP) from restrictive cardiomyopathy (RCM).
  • Lateral (LE') and tricuspid (RE') early diastolic mitral annular velocities (E') in CP have not been thoroughly analyzed against SE'.
  • The influence of pericardial thickness on lateral E' velocity remains unassessed.

Purpose of the Study:

  • To compare early diastolic mitral annular velocities (E')—septal (SE'), lateral (LE'), and tricuspid (RE')—in patients with constrictive pericarditis (CP) and restrictive cardiomyopathy (RCM).
  • To evaluate the relationship between pericardial thickness and lateral E' velocity.

Main Methods:

  • Echocardiography was performed on 37 CP patients, 35 RCM patients, and 70 controls, measuring SE', LE', and RE'.
  • Computed tomography was used to measure maximal pericardial thickness in CP patients.

Main Results:

  • Patients with CP exhibited significantly lower LE'/SE' and RE'/SE' ratios compared to normal controls and RCM patients (p<0.001).
  • A significant inverse correlation was found between right ventricular pericardial thickness and RE' velocity (ρ=-0.489; p=0.002).
  • A trend towards an inverse correlation was observed between left ventricular pericardial thickness and LE' velocity (ρ=-0.284; p=0.089).

Conclusions:

  • Reduced ratios of lateral to septal E' (LE'/SE' and RE'/SE') are valuable diagnostic markers for constrictive pericarditis (CP).
  • Decreased lateral E' velocity correlates with the thickness of the adjacent pericardium.
Abstract

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