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Related Concept Videos

Adhesion01:14

Adhesion

Adhesion occurs when one type of molecule is attracted to a different molecule. Water exhibits adhesive properties in the presence of polar surfaces, such as glass or cellulose in plants. For instance, when water is poured into a glass, the positively charged hydrogen molecules of water are more attracted to the negatively charged oxygen molecules in the silica than to the oxygen in neighboring water molecules.
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Surface Appendages of Archaea

Archaeal surface appendages are highly specialized structures essential for environmental adaptation, encompassing roles in adhesion, biofilm formation, and motility. Among these appendages, pili and archaella stand out for their distinct morphologies and functionalities, enabling archaea to thrive in diverse and often extreme environments.Pili: Adhesion and Biofilm FormationPili are filamentous structures assembled from pilin protein subunits, primarily contributing to adhesion and biofilm...
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Types of Membrane Protrusions

The protrusion of the cell surface is an initial step for several cellular processes, including cell migration, phagocytosis, and neurite outgrowth. These membrane protrusions are a result of cytoskeletal rearrangement. The most  widely observed cell protrusions include lamellipodia, pseudopodia, filopodia, microvilli, invadopodia, and podosomes. These protrusions can be of two types — static or dynamic.
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Cell Migration01:09

Cell Migration

Cell migration, the process by which cells move from one location to another, is essential for the proper development and viability of organisms throughout their life. When cells are not able to migrate properly to their ordained locations, various disorders may occur. For example, disruption in cell migration causes chronic inflammatory diseases such as arthritis.
Cell Migration01:19

Cell Migration

Cell migration is a process by which the cells move from one location to another, playing an essential role in embryological development, repair and regeneration, immune response, and metastasis. Cells migrate in response to chemical or mechanical signals generated by specific organs or tissues. The overall mechanism includes three steps - polarization, protrusion, and release. Polarization involves the formation of a distinct cell front and rear, which determines the direction of movement.
Mechanism of Lamellipodia Formation01:31

Mechanism of Lamellipodia Formation

Cells migrating in response to external stimuli form lamellipodia, which are thin membrane protrusions supported by a mesh of linked, branched, or unbranched actin filaments. These actin filaments interact with myosin motor proteins, creating the dynamic actomyosin complex within the cytoskeleton. Contractility, or the ability to generate contractile stress, is inherent to the actomyosin complex. It helps cells detect the stiffness of the surrounding ECM and exert contractile force for...

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Analyzing Cell Surface Adhesion Remodeling in Response to Mechanical Tension Using Magnetic Beads
07:55

Analyzing Cell Surface Adhesion Remodeling in Response to Mechanical Tension Using Magnetic Beads

Published on: March 8, 2017

Adhesion a la moule.

J Herbert Waite1

  • 1Marine Science Institute, Department Molecular, Cell & Developmental Biology, University of California, Santa Barbara, California 93106.

Integrative and Comparative Biology
|June 18, 2011
PubMed
Summary
This summary is machine-generated.

Mussel adhesive proteins utilize the amino acid DOPA for strong underwater attachment. Optimizing DOPA

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Last Updated: May 31, 2026

Analyzing Cell Surface Adhesion Remodeling in Response to Mechanical Tension Using Magnetic Beads
07:55

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Published on: March 8, 2017

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Area of Science:

  • Biochemistry
  • Materials Science
  • Marine Biology

Background:

  • Mussels exhibit remarkable underwater adhesion in harsh intertidal environments.
  • Their adhesive pads contain multiple proteins rich in 3, 4-dihydroxyphenylalanine (DOPA).

Purpose of the Study:

  • To investigate the role and distribution of DOPA in mussel adhesive proteins.
  • To understand how DOPA influences adhesion and cohesion for marine attachment.

Main Methods:

  • Analysis of protein distribution within mussel adhesive plaques.
  • Examination of DOPA's role in interfacial bonding and cross-linking.

Main Results:

  • Proteins with higher DOPA concentrations (mefp-3, mefp-5) are concentrated at the plaque-substratum interface.
  • DOPA's function extends beyond cross-linking, potentially facilitating direct surface interactions (chemisorption).
  • Balancing DOPA oxidation is key: high oxidation yields cohesion, low oxidation yields adhesion.

Conclusions:

  • Mussel adhesion relies on precise control of DOPA chemistry at the interface.
  • Understanding these adaptations is vital for developing advanced marine adhesives.