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Related Concept Videos

Depolarizing Blockers: Pharmocokinetics01:19

Depolarizing Blockers: Pharmocokinetics

Depolarizing blockers are administered through intravenous injection. Succinylcholine is the most common choice of depolarizing blockers in emergency clinical practices. Although they have a rapid onset, they readily diffuse away from the motor end plate into the extracellular fluid. They are metabolized by enzymes such as liver butyrylcholinesterase and plasma pseudocholinesterases. This produces a short duration of action, typically 5-10 minutes long, unlike nondepolarizing blockers, which...
Local Anesthetics: Clinical Application as Intravenous Regional Anesthesia01:16

Local Anesthetics: Clinical Application as Intravenous Regional Anesthesia

Intravenous regional anesthesia or the Bier block technique is used to anesthetize a specific limb or extremity. It uses exsanguinated or blood-drained vessels to transport local anesthetics or LAs to the peripheral nerve trunks. Lidocaine without vasoconstrictors like epinephrine is most commonly used for this technique. Other drugs used are prilocaine, ropivacaine, and chloroprocaine. Bupivacaine is not recommended for this technique due to its high cardiac toxicity.
One of the advantages of...
Local Anesthetics: Adverse Effects01:12

Local Anesthetics: Adverse Effects

While local anesthetics are generally safe and well-tolerated, they can occasionally cause adverse effects that vary in severity. Local anesthetics can induce toxicity at two distinct levels. They can either produce local effects through direct contact with the neural elements or be absorbed into the bloodstream from the injection site, leading to systemic effects.
Once absorbed into the systemic circulation, local anesthetics can affect the organs that depend on the functioning of sodium...
Local Anesthetics: Clinical Application as Surface, Infiltration, and Conduction Block Anesthesia01:30

Local Anesthetics: Clinical Application as Surface, Infiltration, and Conduction Block Anesthesia

Depending on the target organ, local anesthetics (LAs) can be administered via various routes. In surface anesthesia, LAs are applied directly to the surface of the skin or mucous membranes. It is widely used for topical skin numbing before venipuncture or minor surgical procedures. Commonly used surface local anesthetics are lidocaine or benzocaine sprays or creams. Surface anesthesia occurs within 5 minutes and lasts for about 60 minutes. One of the main disadvantages of topical anesthesia is...
Nondepolarizing (Competitive) Neuromuscular Blockers: Pharmacological Actions01:27

Nondepolarizing (Competitive) Neuromuscular Blockers: Pharmacological Actions

Nondepolarizing neuromuscular blockers prevent the membrane depolarization of muscle cells and inhibit muscle contraction. These are usually administered with anesthetics to achieve complete muscle relaxation. Upon administration, these drugs first block the small, rapidly contracting muscles of the face and hands, followed by the larger muscles of the trunk and the intercostal muscles. The diaphragm is the last muscle to be affected.
Although all competitive neuromuscular blockers are designed...
Nondepolarizing (Competitive) Neuromuscular Blockers: Mechanism of Action01:17

Nondepolarizing (Competitive) Neuromuscular Blockers: Mechanism of Action

Nondepolarizing neuromuscular blockers induce paralysis by competitively blocking nicotinic acetylcholine receptors at the muscle end plate. Examples include pancuronium, mivacurium, vecuronium, and rocuronium. These quaternary ammonium derivatives are administered intravenously, are poorly absorbed, and are excreted via the kidneys.
Competitive antagonists prevent acetylcholine from binding to its receptor, inhibiting membrane depolarization. Without conformational changes or intrinsic...

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Lateral Molar Approach-Driven Transoral Endoscopic Procedure for Benign Infratemporal Fossa Tumor Resection
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Long buccal nerve block: a previously unreported complication.

Marjorie Kerry Herd1, Robert J R Smith, Peter A Brennan

  • 1ST3, Oral and Maxillofacial Surgery, Department of Oral and Maxillofacial Surgery, Queen Alexandra Hospital, Portsmouth, United Kingdom. kerryherd@hotmail.com

Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontics
|June 21, 2011
PubMed
Summary

A rare complication of the long buccal nerve block, involving facial blanching, pain, and paresthesia, has been identified. This adverse event mirrors a previously reported complication from the inferior dental block, highlighting potential vascular risks in dental anesthesia.

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Area of Science:

  • Dentistry
  • Anesthesiology
  • Oral and Maxillofacial Surgery

Background:

  • Local anesthetic injections are routine in dental procedures.
  • Complex facial neurovascular anatomy can lead to unexpected complications.
  • Inferior dental blocks (IDBs) have documented adverse events, unlike typically uneventful long buccal nerve blocks.

Observation:

  • A previously unreported complication following a long buccal nerve block is described.
  • The complication manifested as blanching, pain, and paresthesia.
  • These symptoms occurred specifically within the infraorbital arterial territory.

Findings:

  • The observed complication mirrors an identical event previously reported after an inferior dental block.
  • Facial vascular relationships are discussed as a potential explanation for this shared complication.
  • Management strategies for this specific type of neurovascular compromise are considered.

Implications:

  • This case expands the understanding of potential risks associated with common dental anesthetic techniques.
  • Awareness of these vascular complications is crucial for dental practitioners.
  • Further investigation into facial vascular anatomy and anesthetic injection techniques is warranted to improve patient safety.