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3D-Neuronavigation In Vivo Through a Patient's Brain During a Spontaneous Migraine Headache
10:39

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Published on: June 2, 2014

Persistent unilateral mydriasis and headache.

Mohammad Alkhalil1, Simon Lewis, Matthew Hawker

  • 1Macclesfield General Hospital, Flat 15, The Grange, Ivy Road, Macclesfield SK11 8NA, UK.

BMJ Case Reports
|June 21, 2011
PubMed
Summary
This summary is machine-generated.

A patient initially diagnosed with migraine experienced persistent unilateral headache and anisocoria. Further investigation revealed intermittent angle-closure glaucoma, not migraine, as the cause.

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Area of Science:

  • Ophthalmology
  • Neurology

Background:

  • Migraine headaches can present with unilateral symptoms, including cranial nerve dysfunction.
  • Anisocoria, or unequal pupil size, can be associated with neurological conditions and sometimes with migraine.
  • Misdiagnosis can occur when symptoms overlap between different medical conditions.

Purpose of the Study:

  • To highlight the importance of considering differential diagnoses in patients presenting with unilateral headache and anisocoria.
  • To emphasize the potential for misdiagnosis of intermittent angle-closure glaucoma as migraine.
  • To underscore the need for thorough investigation when symptoms do not resolve as expected.

Main Methods:

  • Case report of a 50-year-old woman with a history of migraine.
  • Initial clinical assessment for unilateral headache and anisocoria.
  • Diagnostic workup prompted by persistent symptoms.

Main Results:

  • Initial assessment suggested migraine-related mydriasis.
  • Persistent symptoms and signs led to further investigation.
  • Diagnosis of intermittent angle-closure glaucoma was confirmed.

Conclusions:

  • Intermittent angle-closure glaucoma can mimic migraine symptoms, including unilateral headache and anisocoria.
  • Failure of symptoms to resolve necessitates re-evaluation and consideration of alternative diagnoses.
  • Ophthalmological examination is crucial in cases of persistent anisocoria and headache.