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A Mouse Model of Incompletely Resected Soft Tissue Sarcoma for Testing (Neo)adjuvant Therapies
Published on: July 28, 2020
Can a chronic expanding haematoma mimic a soft tissue sarcoma?
Moganadass Muniandy1, Vivek Ajit Singh
1University of Malaya, Orthopaedics, Lembah Pantai, Kuala Lumpur, 50603, Malaysia.
BMJ Case Reports
|June 21, 2011
Summary
A gluteal swelling was initially suspected to be soft tissue sarcoma based on clinical and radiological findings. However, surgical resection revealed the swelling was actually a hematoma, highlighting diagnostic challenges.
Area of Science:
- Orthopedics
- Radiology
- Pathology
Background:
- Soft tissue masses in the gluteal region can present diagnostic challenges.
- Distinguishing between neoplastic and non-neoplastic lesions is crucial for appropriate management.
- Imaging modalities play a key role in the initial assessment of soft tissue swellings.
Purpose of the Study:
- To report a case of gluteal swelling initially misdiagnosed as soft tissue sarcoma.
- To emphasize the importance of histopathological examination for definitive diagnosis.
- To discuss the differential diagnosis of gluteal soft tissue masses.
Main Methods:
- Clinical presentation of a 68-year-old woman with a 2-year history of gradually increasing left gluteal swelling.
- Diagnostic workup included clinical examination and radiological imaging.
- Surgical resection of the mass was performed for definitive diagnosis and treatment.
Main Results:
- Clinical and radiological examinations were suggestive of soft tissue sarcoma.
- Histopathological analysis after surgical resection confirmed the diagnosis as hematoma.
- The patient's swelling was ultimately attributed to a collection of blood, not a tumor.
Conclusions:
- Gluteal soft tissue swellings can mimic malignant neoplasms on clinical and radiological assessment.
- Hematoma should be considered in the differential diagnosis of gluteal masses, even with concerning imaging features.
- Surgical resection and subsequent histopathological examination remain the gold standard for diagnosing such conditions.
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