Successful management of intussusception with total polyp clearance in Peutz-Jeghers syndrome using a combined

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Published on: August 22, 2025

Su-San Kong1, Nur Aishah Taib, Sanjiv Mahadeva

  • 1University of Malaya, Surgery, Lembah Pantai, Kuala Lumpur, 50603, Malaysia.

BMJ Case Reports
|June 21, 2011
PubMed

Insights

Intussusception in Peutz-Jeghers syndrome is challenging. A combined surgical and endoscopic approach offers both immediate and long-term success for managing these complex cases.

Area of Science:

  • Gastroenterology and Hepatology
  • Surgical Oncology

Background:

  • Peutz-Jeghers syndrome frequently causes small intestinal polyps, leading to intussusception.
  • Isolated surgical or endoscopic interventions often fail for long-term management of this condition.

Purpose of the Study:

  • To evaluate the efficacy of a combined surgical and endoscopic approach for intussusception management in Peutz-Jeghers syndrome.
  • To highlight the continued relevance of this combined strategy.

Main Methods:

  • A combined approach utilizing both surgical intervention and small bowel endoscopy was employed.
  • This strategy aimed to address intussusception caused by polyps in Peutz-Jeghers syndrome.

Main Results:

  • The combined approach demonstrated both immediate and sustained long-term success.
  • This method effectively managed intussusception in the described cases.

Conclusions:

  • A combined surgical and endoscopic strategy provides effective long-term management for intussusception secondary to Peutz-Jeghers syndrome.
  • This integrated approach remains a valuable option despite advancements in endoscopic technology.

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