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Updated: May 31, 2026

Robotic Duodenal Sleeve Resection for Gastrointestinal Stromal Tumor with Rare Exon 8 KIT Mutation Following Neoadjuvant Imatinib
Published on: April 3, 2026
[Stromal tumors of jejunum and ileum]
O Ciobotaru1, Oana-Roxana Ciobotaru, Cr Dragomir
1Universităţii de Medicină si Farmacie "Gr.T. Popa" Iaşi.
Unlabelled:
Gastrointestinal stromal tumors (GIST) are the most common mesenchymal tumors of the digestive tract and 25% are in the small intestine.
Material And Method:
A retrospective study was performed on 73 patients diagnosed with intestinal cancer in three hospitals in Iasi and Galati, in a period of 12 years (1998-2009).
Results:
Stromal tumors represents 11.5% of malignant tumors of jejunum and ileum, and the average age of diagnosis was 55 years; male to female incidence was 1 : 2 (chi2 = 0.66, p > 0.05). 66.66% of patients came from urban areas (chi2 = 0.66, p > 0.05). The most frequent signs and symptoms were abdominal meteorism and abdominal pain (83%). There were no correlations between admission and discharge diagnosis. CD117 was present in all patients; CD34 was present in 66.66% of them. Survival at 2 years was 66.67% and at 5 years was 33.33%.
Conclusions:
Preoperative diagnosis is often difficult to make, many patients come to doctors in advanced-stage and the five-year survival rate is slow. The most frequent tumor markers were CD117 and CD34.
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