Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Angle Closure Glaucoma: Treatment

Angle Closure Glaucoma: Treatment

Angle-closure glaucoma, or closed-angle glaucoma, is an eye condition where the iris bulges out and blocks the iridocorneal angle, resulting in a buildup of aqueous humor and increased intraocular pressure. Immediate medical attention is necessary due to the sudden onset of symptoms. The treatment for angle-closure glaucoma includes short-term and long-term approaches. Short-term treatment involves using eye drops like pilocarpine to lower intraocular pressure by increasing aqueous humor...

Glaucoma: Overview

Glaucoma: Overview

Glaucoma is an eye condition characterized by increased intraocular pressure that damages the retina and optic nerve, leading to irreversible blindness if left untreated. The human eye has various components, including the cornea, iris, pupil, lens, and optic nerve. Aqueous humor is secreted by the epithelium of the ciliary body in the posterior chamber and flows through the trabecular meshwork and canal of Schlemm, maintaining normal intraocular pressure. The trabecular meshwork and the canal...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Influence of diffractive surface geometry on optical quality and halo formation in sinusoidal trifocal intraocular lenses.

Scientific reports·2026

Same author

Artificial Intelligence Driven Adjusted OCT-Based Classification System for Diabetic Macular Edema (AIDME).

Clinical ophthalmology (Auckland, N.Z.)·2026

Same author

Structural analysis of rhodopsin states in megabody complexes.

Proceedings of the National Academy of Sciences of the United States of America·2026

Same author

Shedding Light on Halos: Quantifying the Impact of the Diffractive Profile in Multifocal Intraocular Lenses.

Translational vision science & technology·2026

Same author

In Vitro Evaluation of Multifocal Intraocular Lenses Based on the Point Spread Function: Optical Performance and Halo Formation.

Journal of clinical medicine·2025

Same author

Aganirsen as a Therapeutic Alternative for Modulating Corneal Neovascularization: A Real-World Case Series Study.

Clinical ophthalmology (Auckland, N.Z.)·2025

Search research articles

Related Experiment Video

Updated: May 31, 2026

Iris Fixation via External Pentagram Suturing

Iris Fixation via External Pentagram Suturing

Published on: May 5, 2022

Acute endothelial failure after cosmetic iris implants (NewIris®).

Maria Garcia-Pous¹, Patricia Udaondo, Salvador Garcia-Delpech

¹Faculty of Medicine, University of Valencia, Valencia, Spain. mgarciapous@gmail.com

Clinical Ophthalmology (Auckland, N.Z.)

|June 22, 2011

Summary

New cosmetic artificial iris implants caused acute endothelial failure, leading to vision loss and pain. These NewIris(®) implants are not a safe alternative to traditional cosmetic contact lenses.

Keywords:

NewIris cosmetic iris implants endothelial failure

More Related Videos

Puncture-Induced Iris Neovascularization as a Mouse Model of Rubeosis Iridis

Puncture-Induced Iris Neovascularization as a Mouse Model of Rubeosis Iridis

Published on: March 8, 2018

An “All-laser” Endothelial Transplant

An “All-laser” Endothelial Transplant

Published on: July 6, 2015

Related Experiment Videos

Last Updated: May 31, 2026

Iris Fixation via External Pentagram Suturing

Iris Fixation via External Pentagram Suturing

Published on: May 5, 2022

Puncture-Induced Iris Neovascularization as a Mouse Model of Rubeosis Iridis

Puncture-Induced Iris Neovascularization as a Mouse Model of Rubeosis Iridis

Published on: March 8, 2018

An “All-laser” Endothelial Transplant

An “All-laser” Endothelial Transplant

Published on: July 6, 2015

Area of Science:

Ophthalmology
Biomaterials Science

Background:

Cosmetic iris implants offer aesthetic enhancement but require rigorous safety evaluation.
The NewIris(®) implant is a novel artificial iris diaphragm for cosmetic purposes.

Observation:

A 21-year-old female presented with progressive vision loss and ocular pain three weeks post-implantation of NewIris(®) lenses.
Clinical examination revealed decreased visual acuity, corneal edema, and elevated intraocular pressure in both eyes.

Findings:

The patient experienced acute endothelial failure, evidenced by a severely reduced corneal endothelial cell count.
Despite prompt removal of the implants, significant and irreversible endothelial damage had occurred.

Implications:

The NewIris(®) implant poses significant risks, including severe endothelial compromise, unlike established phakic anterior chamber intraocular lenses.
This case highlights the potential dangers of cosmetic iris implants and questions their safety and suitability for patients.