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Related Concept Videos

Hemodialysis I: Introduction01:25

Hemodialysis I: Introduction

Hemodialysis (HD) is a medical treatment that artificially removes waste products, excess fluids, and toxins from the blood when the kidneys are no longer able to perform these functions effectively. In this process, blood is filtered through a semipermeable membrane, allowing for the selective removal of waste while preserving necessary components like blood cells and proteins. Hemodialysis is typically performed in patients with end-stage renal disease (ESRD) or severe kidney...
Olfactory Receptors: Location and Structure01:03

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The process of olfaction, also known as the sense of smell, is a sophisticated chemical response system. The specialized sensory neurons that facilitate this process, known as olfactory receptor neurons, are situated in an upper segment of the nasal cavity, known as the olfactory epithelium. Olfactory sensory neurons are bipolar, with their dendrites extending from the epithelium's apex into the mucus that lines the nasal cavity. Airborne molecules, when inhaled, traverse the olfactory...
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Hemodialysis III: Nursing Management01:25

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The nursing management of a patient undergoing hemodialysis includes several critical steps, starting with a thorough assessment before the procedure.Before the Hemodialysis ProcedureFirst, record the patient's vital signs—blood pressure, heart rate, respiratory rate, and temperature—to establish a baseline. This baseline is essential for detecting conditions such as hypotension that could impact the patient's response to dialysis. Document the patient's pre-dialysis weight, as this measurement...
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Measurement of Tissue Oxygenation Using Near-Infrared Spectroscopy in Patients Undergoing Hemodialysis
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Published on: October 2, 2020

Olfactory function improves following hemodialysis.

Basile N Landis1, Nicola Marangon, Patrick Saudan

  • 1Smell and Taste Outpatient Clinic, Department of Otorhinolaryngology Head and Neck Surgery, Bern University Hospital, Inselspital, Bern, Switzerland. bnlandis@yahoo.co.uk

Kidney International
|June 24, 2011
PubMed
Summary
This summary is machine-generated.

Chronic kidney disease (CKD) impairs olfactory function, especially in hemodialysis patients. However, one hemodialysis session significantly improves smell, indicating reversible olfactory dysfunction in CKD patients.

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A Free-breathing fMRI Method to Study Human Olfactory Function
10:42

A Free-breathing fMRI Method to Study Human Olfactory Function

Published on: July 30, 2017

Area of Science:

  • Nephrology
  • Neuroscience
  • Sensory Science

Background:

  • Olfactory dysfunction is reported in chronic kidney disease (CKD), but findings are inconsistent.
  • The impact of dialysis on olfactory function in CKD patients remains unclear.

Purpose of the Study:

  • To investigate olfactory function in CKD patients undergoing hemodialysis or peritoneal dialysis.
  • To determine the effect of dialysis on olfactory function and explore potential correlations with dialysis parameters.

Main Methods:

  • Olfactory function was assessed using smell identification and odor/odorant thresholds in 28 CKD patients and 24 healthy controls.
  • Patients underwent hemodialysis or peritoneal dialysis; pre- and post-dialysis measurements were taken.
  • Dialysis adequacy (Kt/V urea) and body weight changes were recorded.

Main Results:

  • Predialysis olfactory function was significantly reduced in both hemodialysis and peritoneal dialysis patients compared to controls, with hemodialysis patients showing greater impairment.
  • Patients' self-rated olfactory function did not differ from controls, suggesting unawareness of the deficit.
  • A single hemodialysis session led to significant improvement in olfactory function.
  • No correlation was found between olfactory function/improvement and dialysis parameters like BMI or volume loss.

Conclusions:

  • Olfactory dysfunction is prevalent and significant in CKD patients, often unrecognized by the patients themselves.
  • Hemodialysis readily reverses olfactory dysfunction, suggesting reversible peripheral and/or central mechanisms are involved.
  • These findings highlight a treatable consequence of CKD and its treatment.