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Postmenopausal bleeding: causes and risk of genital tract malignancy
Nasira Sabiha Dawood1, Kiran Peter, Faiza Ibrar
1Department of Obstetrics and Gynaecology, Fauji Foundation Hospital/Foundation University Medical College, Rawalpindi, Pakistan. Sobg-nsdawood@cpsp.edu.pk
Journal of Ayub Medical College, Abbottabad : JAMC
|June 28, 2011
Summary
Postmenopausal bleeding (PMB) can indicate serious conditions. This study found that 16.0% of PMB cases were due to genital tract malignancies, highlighting the need for prompt investigation.
Area of Science:
- Gynecology
- Oncology
- Pathology
Background:
- Postmenopausal bleeding (PMB) is defined as bleeding after 6-12 months of amenorrhea in menopausal-aged women.
- It can be a symptom of serious underlying conditions, including genital organ malignancies.
Purpose of the Study:
- To determine the causes and prevalence of genital organ malignancy in women presenting with postmenopausal bleeding.
- To assess the significance of PMB as an indicator of malignancy.
Main Methods:
- A prospective observational study included 167 consecutive patients with postmenopausal bleeding.
- Exclusion criteria included prior hysterectomy, oophorectomy, radiation/chemotherapy, trauma, coagulation disorders, or hormone therapy.
- Data collected included detailed history, clinical examination, and histopathological findings.
Main Results:
- The most frequent cause of PMB was atrophic endometritis and vaginitis (21.2%).
- Genital tract malignancies were found in 16.0% of the cases.
Conclusions:
- The incidence of genital tract malignancies in patients with PMB is notably high (16.0%).
- Postmenopausal bleeding warrants serious attention and prompt, thorough investigation to rule out malignancy.
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