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Updated: Aug 7, 2026

Human Pluripotent Stem Cell Based Developmental Toxicity Assays for Chemical Safety Screening and Systems Biology Data Generation
Published on: June 17, 2015
[Analysis of genotoxic effects of individual factors on chemical industry workers]
Abstract:
The article provides data on the study of occupational and non-occupational factors relating to the prevalence of early spontaneous abortions in couples engaged in fertilizer production. A higher degree prevalence of early spontaneous abortions was detected in several groups affected by specific factors. As this degree of prevalence was found in the groups in which it was only the father that had been exposed to the specific hazardous factors, it was considered that the factors in question either hindered the mutagen tolerance or were capable of their own germ cell mutagen action. It was established that lowered mutagen tolerance related to early abortions was markedly higher in groups exposed to organic substances' compounds and industrial noise.
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