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Updated: May 31, 2026
A Method for Selecting Structure-switching Aptamers Applied to a Colorimetric Gold Nanoparticle Assay
Published on: February 28, 2015
A highly selective and sensitive on-off sensor for silver ions and cysteine by light scattering technique of
Da-Qian Feng1, Guoliang Liu, Wenjie Zheng
1Department of Chemistry, College of Life Science and Technology, Jinan University, Guangzhou 510632, China.
Abstract:
DNA-functionalized gold nanoparticles are shown to act as a light-scattering switch. Ag(+) ion turns on the switch through the DNA-Au NPs conjugates based on the formation of cytosine-Ag(+)-cytosine base pairs, whereas cysteine turns off the light-scattering signal because it competitively binds to Ag(+).
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