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Updated: May 31, 2026

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High-throughput Detection Method for Influenza Virus
Published on: February 4, 2012
Detection of viral nucleoprotein binding to anti-influenza aptamers via SERS
Pierre Negri1, Andreas Kage, Andreas Nitsche
1Department of Chemistry, University of Georgia, Athens, GA 30602, USA. pnegri@uga.edu
Abstract:
A highly sensitive surface-enhanced Raman (SERS)-based method for detection of influenza viral nucleoproteins is described. The intrinsic SERS spectrum of the aptamer-nucleoprotein complex provides direct evidence of binding between a polyvalent anti-influenza aptamer and the nucleoproteins of three influenza strains.

