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Related Concept Videos

Protein Organization01:24

Protein Organization

Proteins are polymers of amino acid residues. They are versatile and responsible for different cellular functions, including DNA replication, molecular transport, catalysis, and structural support. Proteins have a hierarchical structure comprising at least three levels of organization: primary, secondary, and tertiary structure. Some large proteins have a quaternary structure where individual protein subunits are linked together.
The primary structure of a protein is its amino acid sequence.
Protein Organization01:13

Protein Organization

Overview
Protein Organization01:13

Protein Organization

Overview
Protein Organization01:24

Protein Organization

Proteins are polymers of amino acid residues. They are versatile and responsible for different cellular functions, including DNA replication, molecular transport, catalysis, and structural support. Proteins have a hierarchical structure comprising at least three levels of organization: primary, secondary, and tertiary structure. Some large proteins have a quaternary structure where individual protein subunits are linked together.
The primary structure of a protein is its amino acid sequence.
Protein and Protein Structure02:15

Protein and Protein Structure

Proteins are one of the most abundant organic molecules in living systems and have the most diverse range of functions of all macromolecules. Proteins may be structural, regulatory, contractile, or protective. They may serve in transport, storage, or membranes; or they may be toxins or enzymes. Their structures, like their functions, vary greatly. They are all, however, amino acid polymers arranged in a linear sequence.
A protein's shape is critical to its function. For example, an enzyme can...
Protein and Protein Structures02:15

Protein and Protein Structures

Proteins are one of the most abundant organic molecules in living systems and have the most diverse range of functions of all macromolecules. Proteins may be structural, regulatory, contractile, or protective. They may serve in transport, storage, or membranes; or they may be toxins or enzymes. Their structures, like their functions, vary greatly. They are all, however, amino acid polymers arranged in a linear sequence.
A protein's shape is critical to its function. For example, an enzyme can...

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Updated: May 31, 2026

Investigating Protein Sequence-structure-dynamics Relationships with Bio3D-web
09:51

Investigating Protein Sequence-structure-dynamics Relationships with Bio3D-web

Published on: July 16, 2017

An interactive introduction to protein structure.

W Theodore Lee1

  • 1Department of Biology, State University of New York at Fredonia, Fredonia, New York 14063. theodore.lee@fredonia.edu.

Biochemistry and Molecular Biology Education : a Bimonthly Publication of the International Union of Biochemistry and Molecular Biology
|June 28, 2011
PubMed
Summary
This summary is machine-generated.

This project enhances student understanding of protein structure and noncovalent interactions through a hands-on assignment. Students create computer-generated images and papers detailing key interactions in selected protein structures.

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Last Updated: May 31, 2026

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Published on: July 16, 2017

A Protocol for Computer-Based Protein Structure and Function Prediction
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Area of Science:

  • Biochemistry Education
  • Structural Biology

Background:

  • Student comprehension of protein structure and noncovalent interactions can be challenging.
  • Traditional teaching methods may not fully engage students in complex molecular concepts.

Purpose of the Study:

  • To enhance student understanding of protein structure.
  • To elucidate the critical role of noncovalent interactions in protein structure and function.
  • To provide an engaging, hands-on learning experience in biochemistry.

Main Methods:

  • Students undertake a project involving writing a paper.
  • Computer-generated images complement the written work.
  • Students select a protein structure of interest and identify 3-5 key noncovalent interactions.

Main Results:

  • The project facilitates a deeper understanding of protein structural elements.
  • Students gain practical knowledge of how noncovalent interactions stabilize protein structures.
  • The assignment promotes active learning and engagement with biochemical concepts.

Conclusions:

  • This project-based approach effectively improves student grasp of protein structure and noncovalent interactions.
  • Integrating computer-generated imagery enhances visualization and learning.
  • The assignment serves as a valuable pedagogical tool for introductory biochemistry courses.