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Updated: May 31, 2026

Nerve Ultrasound Protocol to Detect Dysimmune Neuropathies
Published on: October 7, 2021
[Case of Heerfordt's syndrome presenting polyneuropathy]
Kumiko Kato1, Yasushi Kato, Yutaka Tanaka
1Department of Ophthalmology, Mie University School of Medicine. 2-174 Edobashi, Tsu-shi, Mie-ken 514-8507, Japan. k-kato@clin.medic.mie-u.ac.jp
Background:
Acute presentation of sarcoidosis with the combination of uveitis, parotid gland enlargement, facial nerve palsy, and fever is called Heerfordt's syndrome. Clinically recognizable involvement of the nervous system occurs in < 10% of patients with sarcoidosis, and polyneuropathy in 24% with neurosarcoidosis.
Case:
A 28-year-old woman diagnosed with Guillain-Barré syndrome was admitted and treated for a month in the Department of Neurology, Mie University hospital. Her visual acuity decreased 2 weeks after discharge. She was admitted to the Department of Ophthalmology, Mie University Hospital. She presented typical optic sarcoidosis. As she had uveitis, facial nerve palsy, parotid gland enlargement and fever in the clinical course, we diagnosed her condition as Heerfordt's syndrome.
Conclusion:
On rare occasions a Heerfordt's syndrome patient may present with Guillain-Barré-like symptoms.
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