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Updated: May 31, 2026

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Imaging Features of Systemic Sclerosis-Associated Interstitial Lung Disease
Published on: June 16, 2020
Elevated MMP-7 levels in patients with systemic sclerosis: correlation with pulmonary involvement
Experimental Dermatology
|June 29, 2011
Summary
Serum MMP-7 levels are elevated in systemic sclerosis (SSc) patients, particularly those with lung fibrosis. This suggests MMP-7 plays a role in fibrotic tissue remodeling in SSc.
Area of Science:
- Biochemistry
- Immunology
- Rheumatology
Background:
- Fibrosis involves excessive connective tissue accumulation due to extracellular matrix imbalance.
- Systemic sclerosis (SSc) is a chronic inflammatory disease causing severe fibrosis in skin and internal organs.