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Updated: May 31, 2026

Molecular Profiling of the Invasive Tumor Microenvironment in a 3-Dimensional Model of Colorectal Cancer Cells and Ex vivo Fibroblasts
10:33

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Published on: April 29, 2014

Recent advances in colorectal cancer research: the microenvironment impact

Anne-Laure Pin1, François Houle, Jacques Huot

  • 1Le Centre de recherche en cancérologie de l'Université Laval, l'Hôtel-Dieu de Québec, Centre de recherche du CHUQ, 9 rue McMahon, Québec, Québec, G1R 2J6, Canada.

Cancer Microenvironment : Official Journal of the International Cancer Microenvironment Society
|June 29, 2011
PubMed
Abstract

No abstract available in PubMed .

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The Tumor Microenvironment02:17

The Tumor Microenvironment

Every normal cell or tissue is embedded in a complex local environment called stroma, consisting of different cell types, a basal membrane, and blood vessels. As normal cells mutate and develop into cancer cells, their local environment also changes to allow cancer progression. The tumor microenvironment (TME) consists of a complex cellular matrix of stromal cells and the developing tumor. The cross-talk between cancer cells and surrounding stromal cells is critical to disrupt normal tissue...
The Tumor Microenvironment02:17

The Tumor Microenvironment

Every normal cell or tissue is embedded in a complex local environment called stroma, consisting of different cell types, a basal membrane, and blood vessels. As normal cells mutate and develop into cancer cells, their local environment also changes to allow cancer progression. The tumor microenvironment (TME) consists of a complex cellular matrix of stromal cells and the developing tumor. The cross-talk between cancer cells and surrounding stromal cells is critical to disrupt normal tissue...