Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Radiological Investigation II: MRI and Ventilation Perfusion Scan01:30

Radiological Investigation II: MRI and Ventilation Perfusion Scan

Description
Magnetic Resonance Imaging (MRI) and Ventilation Perfusion Scans are two radiological investigations that offer detailed diagnostic images of the body, particularly lung structures.
MRI
MRI uses magnetic fields and radiofrequency signals to distinguish between normal and abnormal tissues. This technology provides a more detailed diagnostic image than CT scans, enabling it to characterize pulmonary nodules, stage bronchogenic carcinoma, and evaluate inflammatory activity in...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

The Ritz Adjoint Method for MRI Pulse Design.

IEEE transactions on medical imaging·2026
Same author

Improved, rapid fetal-brain localization and orientation detection for auto-slice prescription.

Proceedings of the International Society for Magnetic Resonance in Medicine ... Scientific Meeting and Exhibition. International Society for Magnetic Resonance in Medicine. Scientific Meeting and Exhibition·2026
Same author

Fast, automated slice prescription of standard anatomical planes for fetal brain MRI.

Proceedings of the International Society for Magnetic Resonance in Medicine ... Scientific Meeting and Exhibition. International Society for Magnetic Resonance in Medicine. Scientific Meeting and Exhibition·2026
Same author

fMRI Using GRAPPA EPI with High Spatial Resolution Improves BOLD Signal Detection at 3T.

The open magnetic resonance reviews·2026
Same author

Mapping subarachnoid cerebrospinal fluid circulation in the human brain.

bioRxiv : the preprint server for biology·2026
Same author

Neural activity drives directional subarachnoid cerebrospinal fluid flow in the human brain.

bioRxiv : the preprint server for biology·2026

Related Experiment Video

Updated: May 31, 2026

Oxygenation-sensitive Cardiac MRI with Vasoactive Breathing Maneuvers for the Non-invasive Assessment of Coronary Microvascular Dysfunction
08:35

Oxygenation-sensitive Cardiac MRI with Vasoactive Breathing Maneuvers for the Non-invasive Assessment of Coronary Microvascular Dysfunction

Published on: August 17, 2022

Phase-based regional oxygen metabolism (PROM) using MRI.

Audrey P Fan1, Thomas Benner, Divya S Bolar

  • 1Research Laboratory of Electronics, Department of Electrical Engineering and Computer Science, Massachusetts Institute of Technology, Cambridge, Massachusetts 02139, USA. apfan@mit.edu

Magnetic Resonance in Medicine
|June 30, 2011
PubMed
Summary

This study introduces a novel MRI technique to measure regional venous oxygen saturation (Y(v)) and cerebral metabolic rate of oxygen (CMRO(2)) noninvasively. This method enables precise quantification of brain oxygenation and metabolism at a local level.

More Related Videos

Magnetic Resonance Imaging Quantification of Pulmonary Perfusion using Calibrated Arterial Spin Labeling
12:29

Magnetic Resonance Imaging Quantification of Pulmonary Perfusion using Calibrated Arterial Spin Labeling

Published on: May 30, 2011

Multi-Tracer Studies of Brain Oxygen and Glucose Metabolism Using a Time-of-Flight Positron Emission Tomography-Computed Tomography Scanner
08:36

Multi-Tracer Studies of Brain Oxygen and Glucose Metabolism Using a Time-of-Flight Positron Emission Tomography-Computed Tomography Scanner

Published on: June 7, 2024

Related Experiment Videos

Last Updated: May 31, 2026

Oxygenation-sensitive Cardiac MRI with Vasoactive Breathing Maneuvers for the Non-invasive Assessment of Coronary Microvascular Dysfunction
08:35

Oxygenation-sensitive Cardiac MRI with Vasoactive Breathing Maneuvers for the Non-invasive Assessment of Coronary Microvascular Dysfunction

Published on: August 17, 2022

Magnetic Resonance Imaging Quantification of Pulmonary Perfusion using Calibrated Arterial Spin Labeling
12:29

Magnetic Resonance Imaging Quantification of Pulmonary Perfusion using Calibrated Arterial Spin Labeling

Published on: May 30, 2011

Multi-Tracer Studies of Brain Oxygen and Glucose Metabolism Using a Time-of-Flight Positron Emission Tomography-Computed Tomography Scanner
08:36

Multi-Tracer Studies of Brain Oxygen and Glucose Metabolism Using a Time-of-Flight Positron Emission Tomography-Computed Tomography Scanner

Published on: June 7, 2024

Area of Science:

  • Neuroimaging
  • Biophysics
  • Medical Physics

Background:

  • Cerebral venous oxygen saturation (Y(v)) and cerebral metabolic rate of oxygen (CMRO(2)) are critical for assessing brain function and disease.
  • Current noninvasive MRI techniques are limited to global measurements, lacking regional quantification capabilities.

Purpose of the Study:

  • To develop and validate a novel, noninvasive MRI technique for quantifying regional venous oxygen saturation (Y(v)) and cerebral metabolic rate of oxygen (CMRO(2)).
  • To enable localized assessment of brain oxygen metabolism using standard MRI sequences.

Main Methods:

  • Utilized gradient-echo and arterial spin labeling MRI sequences for independent estimation of Y(v) and cerebral blood flow (CBF).
  • Employed MR susceptometry on gradient-echo phase images for regional Y(v) quantification in cerebral veins.
  • Applied Fick's principle to calculate local CMRO(2) based on quantified Y(v) and CBF.

Main Results:

  • Successfully quantified regional Y(v), CBF, and CMRO(2) in the gray matter of healthy subjects.
  • Achieved average gray matter values of 59.6% ± 2.3% for Y(v), 51.7 ± 6.4 mL/100 g/min for CBF, and 158 ± 18 micromol/100 g/min for CMRO(2).
  • Results align with previously reported values from positron emission tomography and MRI.

Conclusions:

  • The proposed MRI technique offers a viable noninvasive method for regional quantification of Y(v) and CMRO(2).
  • This advancement facilitates localized assessment of brain oxygen metabolism, crucial for understanding brain function and disease.
  • The method holds promise for improved diagnostic and monitoring capabilities in neurological conditions.