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Updated: May 31, 2026

Evaluation of Left Ventricular Structure and Function using 3D Echocardiography
Published on: October 28, 2020
Real time three-dimensional stress echocardiography: a new approach for assessing diastolic function
Smadar Kort1, Swapna Mamidipally, Purnema Madahar
1Division of Cardiovascular Medicine, Stony Brook University Medical Center, Stony Brook, New York 11794, USA. skort@notes.cc.sunysb.edu
Real-time three-dimensional echocardiography (RT3DE) effectively assesses diastolic function during stress. This method tracks changes in peak ventricular filling rate (PFR) and time to peak filling rate (TPFR), independent of patient demographics.
Area of Science:
- Cardiology
- Echocardiography
- Diastolic Function
Background:
- Assessing diastolic function during stress is crucial for diagnosing heart conditions.
- Traditional methods may have limitations in dynamic stress conditions.
- Real-time three-dimensional echocardiography (RT3DE) offers potential for improved assessment.
Purpose of the Study:
- To evaluate the feasibility of using RT3DE to assess diastolic function under stress.
- To identify key diastolic parameters measurable by RT3DE during stress echocardiography.
Main Methods:
- RT3DE was used to acquire rest and stress volumes in 24 patients.
- Peak ventricular filling rate (PFR) and time to peak filling rate (TPFR) were calculated.
- Correlation analysis was performed between diastolic parameters and hemodynamic variables.
Main Results:
- Diastolic parameter calculation was feasible in all patients.
- Stress significantly increased PFR (93%) and decreased TPFR (23%).
- PFR and TPFR changes correlated with stroke volume, heart rate, and end-systolic volume.
Conclusions:
- RT3DE is a feasible method for assessing diastolic function during stress.
- Changes in PFR and TPFR during stress are influenced by filling pressures.
- Larger studies are needed to confirm the clinical significance of RT3DE in stress diastolic assessment.
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