Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Photoreceptors and Visual Pathways

Photoreceptors and Visual Pathways

At the molecular level, visual signals trigger transformations in photopigment molecules, resulting in changes in the photoreceptor cell's membrane potential. The photon's energy level is denoted by its wavelength, with each specific wavelength of visible light associated with a distinct color. The spectral range of visible light, classified as electromagnetic radiation, spans from 380 to 720 nm. Electromagnetic radiation wavelengths exceeding 720 nm fall under the infrared category, whereas...

Glaucoma: Overview

Glaucoma: Overview

Glaucoma is an eye condition characterized by increased intraocular pressure that damages the retina and optic nerve, leading to irreversible blindness if left untreated. The human eye has various components, including the cornea, iris, pupil, lens, and optic nerve. Aqueous humor is secreted by the epithelium of the ciliary body in the posterior chamber and flows through the trabecular meshwork and canal of Schlemm, maintaining normal intraocular pressure. The trabecular meshwork and the canal...

Angle Closure Glaucoma: Treatment

Angle Closure Glaucoma: Treatment

Angle-closure glaucoma, or closed-angle glaucoma, is an eye condition where the iris bulges out and blocks the iridocorneal angle, resulting in a buildup of aqueous humor and increased intraocular pressure. Immediate medical attention is necessary due to the sudden onset of symptoms. The treatment for angle-closure glaucoma includes short-term and long-term approaches. Short-term treatment involves using eye drops like pilocarpine to lower intraocular pressure by increasing aqueous humor...

Focusing of Light in the Eye

Focusing of Light in the Eye

Light rays enter the eye through the cornea, a transparent dome-shaped tissue that is the eye's outermost layer. The cornea bends or refracts, light rays traveling to the pupil. The shape of the cornea determines how much of the light is bent and whether the image will be focused correctly on the retina at the back of the eye. Once the light has passed through both refraction layers, it converges into a single focal point onto a small area. This is where photoreceptors start transforming...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

The Electrophysiology of Disease Remission in Chronic Inflammatory Demyelinating Polyneuropathy.

European journal of neurology·2026

Same author

Can environmental, social, and governance rating divergence harm the green total factor productivity? Evidence from Chinese listed firms.

Journal of environmental management·2026

Same author

Perspectives on variability of <i>in vivo</i> toxicology studies: considerations for next-generation toxicology.

Frontiers in toxicology·2026

Same author

Total Ankle Arthroplasty vs Arthrodesis in an HbA<sub>1c</sub>-Defined Diabetic Cohort: Lower 1- to 5-Year Structural Complication Rates in a Retrospective Propensity-Matched Study.

Foot & ankle international·2026

Same author

Ten-year functional outcomes and up to 18-year survivorship of computer-navigated total knee arthroplasty: analysis of 1677 cases from a high-volume centre.

European journal of orthopaedic surgery & traumatology : orthopedie traumatologie·2026

Same author

Early transthoracic echocardiography improves in-hospital mortality and fluid resuscitation in septic ICU patients with impaired cardiac function.

Heart & lung : the journal of critical care·2026

Same journal

Rheumatoid arthritis: previously untreated early disease.

BMJ clinical evidence·2016

Same journal

Diabetic retinopathy: intravitreal vascular endothelial growth factor inhibitors for diabetic macular oedema.

BMJ clinical evidence·2016

Same journal

Subarachnoid haemorrhage (spontaneous aneurysmal).

BMJ clinical evidence·2016

Same journal

Malaria: fluid therapy in severe disease.

BMJ clinical evidence·2016

Same journal

Age-related macular degeneration: anti-vascular endothelial growth factor treatment.

BMJ clinical evidence·2016

Same journal

MRSA: treating people with infection.

BMJ clinical evidence·2016

See all related articles

Search research articles

Related Experiment Video

Updated: May 31, 2026

Modeling Cataract Surgery in Mice

Modeling Cataract Surgery in Mice

Published on: December 1, 2023

Cataract.

¹Consultant Eye Surgeon, Sunderland Eye Infirmary, Sunderland, UK.

BMJ Clinical Evidence

|July 2, 2011

Summary

This summary is machine-generated.

Cataract surgery outcomes vary depending on co-existing conditions like glaucoma, diabetic retinopathy, or uveitis. This review evaluates surgical effectiveness and safety for diverse patient groups.

More Related Videos

Rotating the Intraocular Lens to Prevent Posterior Capsular Opacification in Cataract Surgeries

Rotating the Intraocular Lens to Prevent Posterior Capsular Opacification in Cataract Surgeries

Published on: July 7, 2023

Characterization of Molecular Mechanisms of In vivo UVR Induced Cataract

Characterization of Molecular Mechanisms of In vivo UVR Induced Cataract

Published on: November 28, 2012

Related Experiment Videos

Last Updated: May 31, 2026

Modeling Cataract Surgery in Mice

Modeling Cataract Surgery in Mice

Published on: December 1, 2023

Rotating the Intraocular Lens to Prevent Posterior Capsular Opacification in Cataract Surgeries

Rotating the Intraocular Lens to Prevent Posterior Capsular Opacification in Cataract Surgeries

Published on: July 7, 2023

Characterization of Molecular Mechanisms of In vivo UVR Induced Cataract

Characterization of Molecular Mechanisms of In vivo UVR Induced Cataract

Published on: November 28, 2012

Area of Science:

Ophthalmology
Evidence-based medicine

Background:

Cataract is a leading cause of blindness globally, affecting millions.
Cataract surgery in patients with glaucoma may impact glaucoma management.

Purpose of the Study:

To systematically review the effects of cataract surgery in patients with various ocular comorbidities.
To assess cataract surgery outcomes in patients with glaucoma, diabetic retinopathy, and chronic uveitis.

Main Methods:

Systematic review of 20 studies including systematic reviews, RCTs, and observational studies.
Searched major databases (Medline, Embase, Cochrane Library) up to May 2010.
Included harms alerts from regulatory agencies (FDA, MHRA).

Main Results:

Evaluated interventions for cataract patients with no comorbidities.
Assessed cataract surgery effects in patients with co-morbid glaucoma, diabetic retinopathy, and uveitis.
Utilized GRADE methodology to evaluate evidence quality.

Conclusions:

Cataract surgery effectiveness and safety information presented for diverse patient groups.
Interventions reviewed include cataract surgery alone, with glaucoma surgery, and combined treatments.
Management strategies for cataract in conjunction with diabetic retinopathy and uveitis were summarized.