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Published on: February 28, 2012
Warfarin-related nephropathy: another newly recognized complication of an old drug
1Division of Nephrology, Department of Medicine, University of Alabama at Birmingham, Birmingham, Alabama 35294-0007, USA. drizk@uab.edu
Abstract:
Since its approval in the 1950s, warfarin has been the most often prescribed anticoagulant, with attendant risks of bleeding. Brodsky et al. describe another potential complication of warfarin therapy. Warfarin-related nephropathy (WRN) has been described in patients with chronic kidney disease and appears to accelerate the rate of progression and increase the risk of death. The interactions between warfarin and chronic kidney disease are complex, and the recognition of the potential complications is expanding.
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