Related Experiment Video
Updated: May 31, 2026
07:21
Magnetic Resonance Derived Myocardial Strain Assessment Using Feature Tracking
Published on: February 12, 2011
Early myocardial deformation changes associated to isolated obesity: a study based on 3D-wall motion tracking
Adriana Saltijeral1, Leopoldo Pérez de Isla, Olga Pérez-Rodríguez
1Cardiology Department, Hospital Clínico San Carlos, Madrid, Spain.
Obesity (Silver Spring, Md.)
|July 2, 2011
Summary
Obesity in children causes early cardiac changes, including impaired myocardial deformation, detectable by 3D-wall motion tracking echocardiography (3D-WMT). Left ventricular circumferential strain is the most affected parameter, indicating early-stage obesity cardiomyopathy.
Area of Science:
- Pediatric Cardiology
- Cardiovascular Imaging
- Obesity Medicine
Background:
- Obesity is a significant risk factor for cardiovascular disease.
- Early detection of cardiac changes in obese children is crucial.
- 3D-wall motion tracking echocardiography (3D-WMT) assesses left ventricular (LV) myocardial deformation.
Purpose of the Study:
- To evaluate early myocardial deformation abnormalities in obese children.
- To assess these changes in children without other cardiovascular risk factors.
- To identify echocardiographic parameters most affected by childhood obesity.
Main Methods:
- Compared 30 obese children with 42 healthy children.
- Utilized 2D echocardiography and 3D-wall motion tracking echocardiography (3D-WMT).
- Employed multivariate logistic regression to analyze obesity's influence on echocardiographic variables.
Main Results:
- Obese children showed significant differences in LV structure and function compared to controls.
- All 3D-WMT parameters were significantly different between groups.
- LV average circumferential strain demonstrated the strongest association with obesity (β=0.74, P=0.003).
Conclusions:
- Childhood obesity is linked to structural cardiac changes and myocardial deformation abnormalities.
- These changes, indicative of obesity cardiomyopathy, occur early in childhood.
- LV circumferential strain is a key indicator of obesity-related cardiac changes in children.
