Molecular regulatory mechanism of root development

Yee Hung1, Xiaofeng Huang, Yang Chai

  • 1Herman Ostrow School of Dentistry, University of Southern California, USA. yeehung@usc.edu

Summary

Transforming growth factor-beta (TGF-beta) signaling is crucial for tooth development. Eliminating Smad4, a key mediator, in mouse dental epithelium prevents root formation and causes crown defects, highlighting Smad4

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