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[Wilms' tumors in adults].
O Haillot1, F Fetissof, N Suleiman
1Service d'Urologie, C.H.U. Bretonneau, Tours.
Journal D'Urologie
|January 1, 1990
Summary
Adult Wilms
Area of Science:
- Oncology
- Pediatric Oncology
- Nephrology
Background:
- Wilms' tumor, typically a pediatric malignancy, rarely occurs in adults.
- Literature review to understand adult Wilms' tumor pathogenesis and characteristics.
- Comparison with childhood Wilms' tumor to identify unique features.
Observation:
- Presents two adult cases of Wilms' tumor.
- Tumors classified using Kilton's criteria.
- Utilized NWTS 2 staging for treatment stratification.
Findings:
- Adult Wilms' tumors exhibit distinct pathogenetic hypotheses and peculiarities compared to pediatric cases.
- Aggressive treatment strategies appear to improve prognosis.
- Proposed a treatment schedule involving surgery, radiation, and chemotherapy based on tumor staging.
Implications:
- Highlights the importance of recognizing and treating adult Wilms' tumor.
- Suggests aggressive multimodal therapy can enhance outcomes in adult patients.
- Provides a framework for staging and treatment of this rare adult cancer.