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Related Experiment Video

Updated: May 31, 2026

Analyzing and Building Nucleic Acid Structures with 3DNA

Analyzing and Building Nucleic Acid Structures with 3DNA

Published on: April 26, 2013

ModeRNA server: an online tool for modeling RNA 3D structures.

Magdalena Rother¹, Kaja Milanowska, Tomasz Puton

¹Faculty of Biology, Adam Mickiewicz University, ul. Umultowska 89, 61-614 Poznan, Poland.

Bioinformatics (Oxford, England)

|July 6, 2011

Summary

ModeRNA server models three-dimensional RNA structures using comparative methods. This online tool aids in RNA structure analysis, editing, and formatting, enhancing the capabilities of the standalone ModeRNA software.

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Area of Science:

Structural biology
Bioinformatics

Background:

Non-coding RNA molecules play diverse functional roles dictated by their structure.
Accurate RNA 3D structure modeling is crucial for understanding molecular function.

Purpose of the Study:

To introduce the ModeRNA server, an online platform for RNA 3D structure modeling.
To provide users with tools for analyzing, editing, and formatting RNA structure files.

Main Methods:

The ModeRNA server utilizes a comparative modeling approach.
It employs user-defined target-template sequence alignments and template RNA structures.
The server is implemented in Python with the Django web framework.

Main Results:

The ModeRNA server facilitates RNA 3D structure modeling.
It offers template searching capabilities based on target sequences.
The server integrates analysis, editing, and formatting tools for RNA structures.

Conclusions:

The ModeRNA server enhances the functionality of the standalone ModeRNA software.
It provides a user-friendly online environment for RNA structure modeling and analysis.
The tool supports research into the structure-function relationships of non-coding RNAs.