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The Nucleic Acids Circular Dichroism and Fourier Transform Databases NACDDB and NAIRDB: New Tools for RNA Structural

Kevin Mosca1,2,3, Elsa Balduzzi1, Dominik Sordyl4

  • 1Laboratoire Léon Brillouin LLB, CEA, CNRS UMR 12, CEA Saclay, Gif-sur-Yvette, France.

Methods in Molecular Biology (Clifton, N.J.)
|January 1, 2026
PubMed
Summary

Two new databases, NACDDB and NAIRDB, offer comprehensive Circular Dichroism (CD) and Fourier Transform Infrared (FTIR) spectroscopic datasets for nucleic acids (NA). These resources aid researchers in studying NA conformations and structural dynamics.

Keywords:
Base stacking and pairingChiro-optical spectroscopyHelical propertiesSugar pucker, RNA secondary structure, Spectroscopic databaseVibrational spectroscopy

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