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Published on: November 10, 2016
Type I collagen-templated assembly of silver nanoparticles and their application in surface-enhanced Raman scattering
Yujing Sun1, Gang Wei, Yonghai Song
1State Key Lab of Electroanalytical Chemistry, Changchun Institute of Applied Chemistry, Graduate School of the Chinese Academy of Sciences, Chinese Academy of Sciences, Changchun 130022, People's Republic of China.
Abstract:
Silver nanoparticles (Ag NPs) are one of the active substrates that are employed extensively in surface-enhanced Raman scattering (SERS), and aggregations of Ag NPs play an important role in enhancing the Raman signals. In this paper, we fabricated two kinds of SERS-active substrates utilizing the electrostatic adsorption and superior assembly properties of type I collagen. These were collagen-Ag NP aggregation films and nanoporous Ag films. Two probe molecules, 4-aminothiophenol (4-ATP) and methylene blue (MB), were studied on these substrates. These substrates showed reproducible SERS intensities with relative standard deviations (RSDs) of 8-10% and 11-14%, respectively, while the RSDs of the traditional thick Ag films were 12-28%. Also, the intensities for the 4-ATP spectrum on the collagen-templated nanoporous Ag film were approximately one order higher than those on the DNA-templated Ag film.
