Related Experiment Video

Updated: May 31, 2026

Simplified Whole Body Plethysmography to Characterize Lung Function During Respiratory Melioidosis
07:27

Simplified Whole Body Plethysmography to Characterize Lung Function During Respiratory Melioidosis

Published on: February 24, 2023

Melioidosis: a case report

Purabi Barman1, Harish Sidhwa, Pinak A Shirkhande

  • 1Super Religare Laboratories Ltd, Fortis Flt. Rajan Dhall Hospital, Vasant Kunj, New Delhi, India.

Journal of Global Infectious Diseases
|July 7, 2011
PubMed

Insights

Burkholderia pseudomallei is an emerging pathogen in India, causing diverse infections. This case highlights successful treatment of a severe infection with Imipenem and Doxycycline.

Area of Science:

  • Medical Microbiology
  • Infectious Diseases

Background:

  • Burkholderia pseudomallei is an emerging pathogen in India, primarily reported in the southern regions.
  • It causes a range of clinical manifestations including pneumonia, septicaemia, arthritis, and abscesses.

Observation:

  • A 65-year-old male presented with a month-long history of fever, cough, and breathlessness.
  • Swelling in both ankles was noted for seven days prior to presentation.
  • The patient had B. pseudomallei isolated from endotracheal secretions, blood cultures, and a leg wound.

Findings:

  • The patient was diagnosed with a severe B. pseudomallei infection.
  • Successful treatment was achieved using a combination of Imipenem and Doxycycline.
  • The patient is currently on maintenance therapy and recovering well.

Implications:

  • This case underscores the growing importance of B. pseudomallei in India.
  • Prompt diagnosis and appropriate antibiotic therapy are crucial for favorable outcomes.
  • Further surveillance and research are needed to understand the epidemiology and management of melioidosis in India.
Keywords:
Burkhlorderia pseudomalleiImipenemMelioidosisSepticaemia

Related Concept Videos

Leishmaniasis01:30

Leishmaniasis

Leishmaniasis is a protozoal disease caused by species of the genus Leishmania and transmitted through the bite of infected female sandflies. The parasite exists in two principal morphological forms during its life cycle. A sandfly acquires intracellular amastigotes from an infected reservoir host, such as a dog. Within the sandfly, these forms differentiate into motile, flagellated promastigotes. During a subsequent blood meal, promastigotes are injected into the human host, where they...
Rocky Mountain Spotted Fever01:26

Rocky Mountain Spotted Fever

Rocky Mountain Spotted Fever (RMSF) is a severe tick-borne illness caused by Rickettsia rickettsii, a Gram-negative, coccobacillary bacterium. This pathogen is an obligate intracellular parasite, requiring a host cell for replication. Transmission occurs through the bite of an infected tick. In the United States, the most important vectors are Dermacentor variabilis (American dog tick) and Dermacentor andersoni (Rocky Mountain wood tick), though other tick species may also serve as vectors.