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Updated: May 31, 2026

Enzymatic Cascade Reactions for the Synthesis of Chiral Amino Alcohols from L-lysine
Published on: February 16, 2018
The organocatalytic vinylogous aldol reaction: recent advances
Sunil V Pansare1, Eldho K Paul
1Department of Chemistry, Memorial University, St. John's, Newfoundland, Canada. spansare@mun.ca
Abstract:
Over the past decade, organocatalysis has emerged as a powerful tool for stereoselective carbon-carbon bond formation under exceptionally mild conditions. The organocatalytic versions of a large number of traditional synthetic transformations are now well established and the quest for new applications of the basic concepts of organocatalysis continues. This review addresses the emergent interest in the organocatalytic vinylogous aldol reaction. While noteworthy progress has been made in this area, significant challenges lie ahead.
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