Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Karyotyping01:17

Karyotyping

Overview
Immunocytochemistry and Immunohistochemistry01:22

Immunocytochemistry and Immunohistochemistry

Immunocytochemistry (ICC) and immunohistochemistry (IHC) are techniques that use antibodies to check for specific proteins or antigens in a sample. The technique was first published by Albert Coons in 1941 to detect the presence of pneumococcal antigen in tissue sections from mice infected with Pneumococcus. Immunocytochemistry helps localization of proteins or antigens in individual cells like blood cells, stem cells, etc., while immunohistochemistry does the same for tissue samples.
These...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Interpretive Diagnostic Error Reduction: Guideline Update from the College of American Pathologists in Collaboration With the Association of Directors of Anatomic and Subspecialty Pathology.

Archives of pathology & laboratory medicine·2026
Same author

Clinical Faceoff: Should Routine Histopathological Analysis be Performed on Specimens Obtained During Primary Arthroplasty Surgery?

Clinical orthopaedics and related research·2019
Same author

Corrigendum to "Precancerous cervical lesions and HPV genotypes identified in previously unsatisfactory cervical smear tests after inexpensive glacial acetic acid processing" [Int J Gynecol Obstet 2018. doi: 10.1002/ijgo.12699.].

International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics·2019
Same author

Precancerous cervical lesions and HPV genotypes identified in previously unsatisfactory cervical smear tests after inexpensive glacial acetic acid processing.

International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics·2018
Same author

Human papillomavirus screening for low and middle-income countries.

Preventive medicine·2017
Same author

Interpretive Diagnostic Error Reduction in Surgical Pathology and Cytology: Guideline From the College of American Pathologists Pathology and Laboratory Quality Center and the Association of Directors of Anatomic and Surgical Pathology.

Archives of pathology & laboratory medicine·2015
Same journal

New progress in addressing cancer pain: Recent studies have offered revealing insights into predisposing, precipitating, and perpetuating factors as well as underlying mechanisms and potential interventions.

Cancer cytopathology·2026
Same journal

Molecular profiling of breast cancer pleural effusions using cytology specimens: Impact of sample source and cytological features on next-generation sequencing performance.

Cancer cytopathology·2026
Same journal

Accurate focal-plane selection is crucial for artificial intelligence assessment of three-dimensional urine cytology specimens for bladder cancer screening and surveillance.

Cancer cytopathology·2026
Same journal

Application of the International System for Serous Fluid Cytopathology in cerebrospinal fluid cytology: Overall survival analysis associated with diagnostic categories.

Cancer cytopathology·2026
Same journal

The performance of intraoperative peritoneal washings in detecting pancreatic ductal adenocarcinoma.

Cancer cytopathology·2026
Same journal

Supernatant: What's in a name?

Cancer cytopathology·2026
See all related articles

Related Experiment Video

Updated: May 31, 2026

Tubal Cytology of the Fallopian Tube as a Promising Tool for Ovarian Cancer Early Detection
08:09

Tubal Cytology of the Fallopian Tube as a Promising Tool for Ovarian Cancer Early Detection

Published on: July 25, 2017

Cytologic-histologic correlation.

Stephen S Raab1, Dana M Grzybicki

  • 1Department of Pathology, University of Colorado, Aurora, Colorado 80045, USA. raabss@gmail.com

Cancer Cytopathology
|July 7, 2011
PubMed
Summary
This summary is machine-generated.

Cytologic-histologic correlation improves diagnostic accuracy, particularly through better Papanicolaou (Pap) test sampling. Continuous data tracking aids in refining screening processes for enhanced patient safety.

More Related Videos

Enhancing Prostate Tumor Biobanking Reliability with Improved Sampling Technique and Histological Characterization
07:34

Enhancing Prostate Tumor Biobanking Reliability with Improved Sampling Technique and Histological Characterization

Published on: November 17, 2023

Generating and Analyzing High-Parameter Histology Images with Histoflow Cytometry
05:22

Generating and Analyzing High-Parameter Histology Images with Histoflow Cytometry

Published on: June 21, 2024

Related Experiment Videos

Last Updated: May 31, 2026

Tubal Cytology of the Fallopian Tube as a Promising Tool for Ovarian Cancer Early Detection
08:09

Tubal Cytology of the Fallopian Tube as a Promising Tool for Ovarian Cancer Early Detection

Published on: July 25, 2017

Enhancing Prostate Tumor Biobanking Reliability with Improved Sampling Technique and Histological Characterization
07:34

Enhancing Prostate Tumor Biobanking Reliability with Improved Sampling Technique and Histological Characterization

Published on: November 17, 2023

Generating and Analyzing High-Parameter Histology Images with Histoflow Cytometry
05:22

Generating and Analyzing High-Parameter Histology Images with Histoflow Cytometry

Published on: June 21, 2024

Area of Science:

  • Pathology
  • Cytopathology
  • Surgical Pathology

Background:

  • Cytologic-histologic correlation is crucial for advancing cytopathology and surgical pathology.
  • Correlation yields valuable data for enhancing diagnostic testing and screening protocols.
  • Previous studies highlight the impact of correlation on diagnostic quality.

Purpose of the Study:

  • To analyze the impact of cytologic-histologic correlation on diagnostic quality improvement.
  • To identify key factors driving improvements in diagnostic testing and screening processes.
  • To explore the role of liquid-based cytology and data analysis in quality enhancement.

Main Methods:

  • Continuous data tracking and retrospective root cause analysis were employed.
  • Evaluation of performance indicators related to Papanicolaou (Pap) test sampling sensitivity.
  • Analysis of institutional participation duration and its effect on sampling quality.

Main Results:

  • Overall diagnostic improvement was significantly linked to enhanced preanalytic Pap test sampling.
  • Increased institutional participation correlated with improved sampling sensitivity.
  • Introduction of liquid-based cytology technology may have contributed to sampling improvements.

Conclusions:

  • Cytologic-histologic correlation is a vital tool for quality improvement in pathology.
  • Standardization of methods and rigorous root cause analysis are essential for future progress.
  • Active utilization of correlation data can optimize testing and screening for patient safety.